MUC1 Tissue Expression and Its Soluble Form CA15-3 Identify a Clear Cell Renal Cell Carcinoma with Distinct Metabolic Profile and Poor Clinical Outcome

MUC1 Tissue Expression and Its Soluble Form CA15-3 Identify a Clear Cell Renal Cell Carcinoma with Distinct Metabolic Profile and Poor Clinical Outcome

An altered metabolism is involved in the development of clear cell renal carcinoma (ccRCC). MUC1 overexpression has been found to be associated with advanced disease and poor prognosis. In this study, we evaluated the metabolomic profile of human ccRCC, according to MUC1 expression, and integrated i...

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Bibliographic Details
Main Authors: Giuseppe Lucarelli, Monica Rutigliano, Davide Loizzo, Nicola Antonio di Meo, Francesco Lasorsa, Mauro Mastropasqua, Eugenio Maiorano, Cinzia Bizzoca, Leonardo Vincenti, Michele Battaglia, Pasquale Ditonno
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:International Journal of Molecular Sciences
Subjects:
renal cell carcinoma
metabolomics
MUC1
CA15-3
survival
Online Access:https://www.mdpi.com/1422-0067/23/22/13968

Internet

https://www.mdpi.com/1422-0067/23/22/13968

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