Wnt-controlled sphingolipids modulate Anthrax Toxin Receptor palmitoylation to regulate oriented mitosis in zebrafish
During development, oriented cell division is important to proper body axis extension. Here, the authors show that sphingolipids are required to direct spindle rotation and oriented mitosis via Anthrax receptor palmitoylation in zebrafish gastrulation.
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2020-07-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-020-17196-3 |
| _version_ | 1818428365380517888 |
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| author | I. Castanon J. T. Hannich L. Abrami F. Huber M. Dubois M. Müller F. G. van der Goot M. Gonzalez-Gaitan |
| author_facet | I. Castanon J. T. Hannich L. Abrami F. Huber M. Dubois M. Müller F. G. van der Goot M. Gonzalez-Gaitan |
| author_sort | I. Castanon |
| collection | DOAJ |
| description | During development, oriented cell division is important to proper body axis extension. Here, the authors show that sphingolipids are required to direct spindle rotation and oriented mitosis via Anthrax receptor palmitoylation in zebrafish gastrulation. |
| first_indexed | 2024-12-14T15:00:28Z |
| format | Article |
| id | doaj.art-8a8ca64a3ec14891b6839f3bf319ba3c |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-14T15:00:28Z |
| publishDate | 2020-07-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-8a8ca64a3ec14891b6839f3bf319ba3c2022-12-21T22:56:52ZengNature PortfolioNature Communications2041-17232020-07-0111111410.1038/s41467-020-17196-3Wnt-controlled sphingolipids modulate Anthrax Toxin Receptor palmitoylation to regulate oriented mitosis in zebrafishI. Castanon0J. T. Hannich1L. Abrami2F. Huber3M. Dubois4M. Müller5F. G. van der Goot6M. Gonzalez-Gaitan7Department of Biochemistry and NCCR Chemical Biology, 30 Quai Ernest-AnsermetDepartment of Biochemistry and NCCR Chemical Biology, 30 Quai Ernest-AnsermetGlobal Health Institute, EPFL, Station 15Vital-IT, SIB Swiss Institute of BioinformaticsDepartment of Biochemistry and NCCR Chemical Biology, 30 Quai Ernest-AnsermetVital-IT, SIB Swiss Institute of BioinformaticsGlobal Health Institute, EPFL, Station 15Department of Biochemistry and NCCR Chemical Biology, 30 Quai Ernest-AnsermetDuring development, oriented cell division is important to proper body axis extension. Here, the authors show that sphingolipids are required to direct spindle rotation and oriented mitosis via Anthrax receptor palmitoylation in zebrafish gastrulation.https://doi.org/10.1038/s41467-020-17196-3 |
| spellingShingle | I. Castanon J. T. Hannich L. Abrami F. Huber M. Dubois M. Müller F. G. van der Goot M. Gonzalez-Gaitan Wnt-controlled sphingolipids modulate Anthrax Toxin Receptor palmitoylation to regulate oriented mitosis in zebrafish Nature Communications |
| title | Wnt-controlled sphingolipids modulate Anthrax Toxin Receptor palmitoylation to regulate oriented mitosis in zebrafish |
| title_full | Wnt-controlled sphingolipids modulate Anthrax Toxin Receptor palmitoylation to regulate oriented mitosis in zebrafish |
| title_fullStr | Wnt-controlled sphingolipids modulate Anthrax Toxin Receptor palmitoylation to regulate oriented mitosis in zebrafish |
| title_full_unstemmed | Wnt-controlled sphingolipids modulate Anthrax Toxin Receptor palmitoylation to regulate oriented mitosis in zebrafish |
| title_short | Wnt-controlled sphingolipids modulate Anthrax Toxin Receptor palmitoylation to regulate oriented mitosis in zebrafish |
| title_sort | wnt controlled sphingolipids modulate anthrax toxin receptor palmitoylation to regulate oriented mitosis in zebrafish |
| url | https://doi.org/10.1038/s41467-020-17196-3 |
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