BRAF and NRAS Mutations in Papillary Thyroid Carcinoma and Concordance in BRAF Mutations Between Primary and Corresponding Lymph Node Metastases

BRAF and NRAS Mutations in Papillary Thyroid Carcinoma and Concordance in BRAF Mutations Between Primary and Corresponding Lymph Node Metastases

Abstract Concordance between mutations in the primary papillary thyroid carcinoma (PTC) and the paired x lymph node metastasis may elucidate the potential role of molecular targeted therapy in advanced stages. BRAF and NRAS mutations in primary PTC (n = 253) with corresponding metastatic lymph node...

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Bibliographic Details
Main Authors: Najla Fakhruddin, Mark Jabbour, Michael Novy, Hani Tamim, Hisham Bahmad, Fadi Farhat, Ghazi Zaatari, Tarek Aridi, Gernot Kriegshauser, Christian Oberkanins, Rami Mahfouz
Format: Article
Language:English
Published: Nature Portfolio 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-04948-3

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