Prevalence of Vitamin D Deficiency and Rickets in Children with Cholestasis in Iran
This study was aimed to determine prevalence of Vitamin D deficiency and rickets in children with cholestatic liver diseases. Forty eight children with established cholestatic liver disease who referred to gastrointestinal clinic of Children Medical Center (Tehran, Iran) between April 2010 and March...
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2012-07-01
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| Series: | Acta Medica Iranica |
| Subjects: | |
| Online Access: | http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/21705.pdf&manuscript_id=21705 |
| _version_ | 1818851056416718848 |
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| author | Mohammad Eshagh Roze Jamshid Mohammadi Mahsa Ghajarzadeh Farzaneh Motamed Fateme Farahmand Mehri Najafi Bahram Mohammadi |
| author_facet | Mohammad Eshagh Roze Jamshid Mohammadi Mahsa Ghajarzadeh Farzaneh Motamed Fateme Farahmand Mehri Najafi Bahram Mohammadi |
| author_sort | Mohammad Eshagh Roze |
| collection | DOAJ |
| description | This study was aimed to determine prevalence of Vitamin D deficiency and rickets in children with cholestatic liver diseases. Forty eight children with established cholestatic liver disease who referred to gastrointestinal clinic of Children Medical Center (Tehran, Iran) between April 2010 and March 2011 were enrolled in a cross-sectional study. Laboratory analysis including calcium, phosphate, albumin, total and direct bilirubin, aminotransferases, alkalinephosphatase (ALP), prothrombin time (PT), parathyroid hormone (PTH), total protein determined by routine laboratory techniques. Mean age of participants was 299.1 ± 676.8 days (range 2-3600 days) whereas twenty one were female (43.8%) and 27 (56.3%) were male. Twenty two (45.8%) had evidences of rickets in X-ray evaluation. Three children with rickets and two with normal X-ray had Vitamin D deficiency while ten in rickets group and 16 in normal group had Vitamin D insufficiency. The main underlying diseases were anatomical biliary atresia in cases with rickets and idiopathic in other group. Rickets and Vitamin D deficiency should be considered in chronic cholestatic children. |
| first_indexed | 2024-12-19T06:58:57Z |
| format | Article |
| id | doaj.art-8a92dda3c7934207aa3f27e3536b85f3 |
| institution | Directory Open Access Journal |
| issn | 0044-6025 0173-5969 |
| language | English |
| last_indexed | 2024-12-19T06:58:57Z |
| publishDate | 2012-07-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Acta Medica Iranica |
| spelling | doaj.art-8a92dda3c7934207aa3f27e3536b85f32022-12-21T20:31:27ZengTehran University of Medical SciencesActa Medica Iranica0044-60250173-59692012-07-01507482485Prevalence of Vitamin D Deficiency and Rickets in Children with Cholestasis in IranMohammad Eshagh RozeJamshid MohammadiMahsa GhajarzadehFarzaneh MotamedFateme FarahmandMehri NajafiBahram MohammadiThis study was aimed to determine prevalence of Vitamin D deficiency and rickets in children with cholestatic liver diseases. Forty eight children with established cholestatic liver disease who referred to gastrointestinal clinic of Children Medical Center (Tehran, Iran) between April 2010 and March 2011 were enrolled in a cross-sectional study. Laboratory analysis including calcium, phosphate, albumin, total and direct bilirubin, aminotransferases, alkalinephosphatase (ALP), prothrombin time (PT), parathyroid hormone (PTH), total protein determined by routine laboratory techniques. Mean age of participants was 299.1 ± 676.8 days (range 2-3600 days) whereas twenty one were female (43.8%) and 27 (56.3%) were male. Twenty two (45.8%) had evidences of rickets in X-ray evaluation. Three children with rickets and two with normal X-ray had Vitamin D deficiency while ten in rickets group and 16 in normal group had Vitamin D insufficiency. The main underlying diseases were anatomical biliary atresia in cases with rickets and idiopathic in other group. Rickets and Vitamin D deficiency should be considered in chronic cholestatic children.http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/21705.pdf&manuscript_id=21705RicketsVitamin DChronic cholestasisChildren |
| spellingShingle | Mohammad Eshagh Roze Jamshid Mohammadi Mahsa Ghajarzadeh Farzaneh Motamed Fateme Farahmand Mehri Najafi Bahram Mohammadi Prevalence of Vitamin D Deficiency and Rickets in Children with Cholestasis in Iran Acta Medica Iranica Rickets Vitamin D Chronic cholestasis Children |
| title | Prevalence of Vitamin D Deficiency and Rickets in Children with Cholestasis in Iran |
| title_full | Prevalence of Vitamin D Deficiency and Rickets in Children with Cholestasis in Iran |
| title_fullStr | Prevalence of Vitamin D Deficiency and Rickets in Children with Cholestasis in Iran |
| title_full_unstemmed | Prevalence of Vitamin D Deficiency and Rickets in Children with Cholestasis in Iran |
| title_short | Prevalence of Vitamin D Deficiency and Rickets in Children with Cholestasis in Iran |
| title_sort | prevalence of vitamin d deficiency and rickets in children with cholestasis in iran |
| topic | Rickets Vitamin D Chronic cholestasis Children |
| url | http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/21705.pdf&manuscript_id=21705 |
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