Role of the circadian clock in the statistics of locomotor activity in Drosophila.
In many animals the circadian rhythm of locomotor activity is controlled by an endogenous circadian clock. Using custom made housing and video tracking software in order to obtain high spatial and temporal resolution, we studied the statistical properties of the locomotor activity of wild type and t...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2018-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC6107170?pdf=render |
| _version_ | 1818258916060954624 |
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| author | Guadalupe Cascallares Sabrina Riva D Lorena Franco Sebastian Risau-Gusman Pablo M Gleiser |
| author_facet | Guadalupe Cascallares Sabrina Riva D Lorena Franco Sebastian Risau-Gusman Pablo M Gleiser |
| author_sort | Guadalupe Cascallares |
| collection | DOAJ |
| description | In many animals the circadian rhythm of locomotor activity is controlled by an endogenous circadian clock. Using custom made housing and video tracking software in order to obtain high spatial and temporal resolution, we studied the statistical properties of the locomotor activity of wild type and two clock mutants of Drosophila melanogaster. We show here that the distributions of activity and quiescence bouts for the clock mutants in light-dark conditions (LD) are very different from the distributions obtained when there are no external cues from the environment (DD). In the wild type these distributions are very similar, showing that the clock controls this aspect of behavior in both regimes (LD and DD). Furthermore, the distributions are very similar to those reported for Wistar rats. For the timing of events we also observe important differences, quantified by how the event rate distributions scale for increasing time windows. We find that for the wild type these distributions can be rescaled by the same function in DD as in LD. Interestingly, the same function has been shown to rescale the rate distributions in Wistar rats. On the other hand, for the clock mutants it is not possible to rescale the rate distributions, which might indicate that the extent of circadian control depends on the statistical properties of activity and quiescence. |
| first_indexed | 2024-12-12T18:07:08Z |
| format | Article |
| id | doaj.art-8a94d4e910f7417086216bd0ad9aee27 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-12T18:07:08Z |
| publishDate | 2018-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-8a94d4e910f7417086216bd0ad9aee272022-12-22T00:16:28ZengPublic Library of Science (PLoS)PLoS ONE1932-62032018-01-01138e020250510.1371/journal.pone.0202505Role of the circadian clock in the statistics of locomotor activity in Drosophila.Guadalupe CascallaresSabrina RivaD Lorena FrancoSebastian Risau-GusmanPablo M GleiserIn many animals the circadian rhythm of locomotor activity is controlled by an endogenous circadian clock. Using custom made housing and video tracking software in order to obtain high spatial and temporal resolution, we studied the statistical properties of the locomotor activity of wild type and two clock mutants of Drosophila melanogaster. We show here that the distributions of activity and quiescence bouts for the clock mutants in light-dark conditions (LD) are very different from the distributions obtained when there are no external cues from the environment (DD). In the wild type these distributions are very similar, showing that the clock controls this aspect of behavior in both regimes (LD and DD). Furthermore, the distributions are very similar to those reported for Wistar rats. For the timing of events we also observe important differences, quantified by how the event rate distributions scale for increasing time windows. We find that for the wild type these distributions can be rescaled by the same function in DD as in LD. Interestingly, the same function has been shown to rescale the rate distributions in Wistar rats. On the other hand, for the clock mutants it is not possible to rescale the rate distributions, which might indicate that the extent of circadian control depends on the statistical properties of activity and quiescence.http://europepmc.org/articles/PMC6107170?pdf=render |
| spellingShingle | Guadalupe Cascallares Sabrina Riva D Lorena Franco Sebastian Risau-Gusman Pablo M Gleiser Role of the circadian clock in the statistics of locomotor activity in Drosophila. PLoS ONE |
| title | Role of the circadian clock in the statistics of locomotor activity in Drosophila. |
| title_full | Role of the circadian clock in the statistics of locomotor activity in Drosophila. |
| title_fullStr | Role of the circadian clock in the statistics of locomotor activity in Drosophila. |
| title_full_unstemmed | Role of the circadian clock in the statistics of locomotor activity in Drosophila. |
| title_short | Role of the circadian clock in the statistics of locomotor activity in Drosophila. |
| title_sort | role of the circadian clock in the statistics of locomotor activity in drosophila |
| url | http://europepmc.org/articles/PMC6107170?pdf=render |
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