JUVENILE XANTHOGRANULOMA: A CASE REPORT

ABSTRACT Objective: To report a rate case of Juvenile xanthogranuloma in a newborn infant. Case description: We present the case of a 31-week preterm newborn with multiple skin lesions whose clinical, histological and immunohistochemical findings allowed the diagnosis of juvenile xanthogranuloma...

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Main Authors: Sara Pires da Silva, Catarina Viveiros, Rui Almeida, Marta Almeida Pereira, Rute Vaz, Alexandrina Portela
Format: Article
Language:English
Published: Sociedade de Pediatria de São Paulo 2019-02-01
Series:Revista Paulista de Pediatria
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-05822019005004106&lng=en&tlng=en
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author Sara Pires da Silva
Catarina Viveiros
Rui Almeida
Marta Almeida Pereira
Rute Vaz
Alexandrina Portela
author_facet Sara Pires da Silva
Catarina Viveiros
Rui Almeida
Marta Almeida Pereira
Rute Vaz
Alexandrina Portela
author_sort Sara Pires da Silva
collection DOAJ
description ABSTRACT Objective: To report a rate case of Juvenile xanthogranuloma in a newborn infant. Case description: We present the case of a 31-week preterm newborn with multiple skin lesions whose clinical, histological and immunohistochemical findings allowed the diagnosis of juvenile xanthogranuloma. Currently, the patient has nine months-old, and there is no aggravation of the skin lesions or evidence of extra-cutaneous involvement, particularly ophthalmic. Comments: Juvenile xanthogranuloma is a rare and benign condition, included in the vast group of non-Langerhans histiocytosis. It typically occurs in the pediatric age and may have a neonatal presentation. It affects predominantly the skin, in the form of papules or yellow and/or erythematous nodules and could be asymptomatic, multiple or solitary. Extra-cutaneous involvement, is more common in toddlers and when multiple lesions are present. The eye is the most affected site. We highlight this clinical case by its presentation in the neonatal period and in the form of multiple lesions, which bestows an increased risk of extra-cutaneous involvement, although this has not yet been verified.
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spelling doaj.art-8a9583d0d6134aed8aae76e7c517b01c2022-12-21T23:35:33ZengSociedade de Pediatria de São PauloRevista Paulista de Pediatria1984-04622019-02-01010.1590/1984-0462/;2019;37;2;00013S0103-05822019005004106JUVENILE XANTHOGRANULOMA: A CASE REPORTSara Pires da SilvaCatarina ViveirosRui AlmeidaMarta Almeida PereiraRute VazAlexandrina PortelaABSTRACT Objective: To report a rate case of Juvenile xanthogranuloma in a newborn infant. Case description: We present the case of a 31-week preterm newborn with multiple skin lesions whose clinical, histological and immunohistochemical findings allowed the diagnosis of juvenile xanthogranuloma. Currently, the patient has nine months-old, and there is no aggravation of the skin lesions or evidence of extra-cutaneous involvement, particularly ophthalmic. Comments: Juvenile xanthogranuloma is a rare and benign condition, included in the vast group of non-Langerhans histiocytosis. It typically occurs in the pediatric age and may have a neonatal presentation. It affects predominantly the skin, in the form of papules or yellow and/or erythematous nodules and could be asymptomatic, multiple or solitary. Extra-cutaneous involvement, is more common in toddlers and when multiple lesions are present. The eye is the most affected site. We highlight this clinical case by its presentation in the neonatal period and in the form of multiple lesions, which bestows an increased risk of extra-cutaneous involvement, although this has not yet been verified.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-05822019005004106&lng=en&tlng=enXanthogranuloma, juvenileHistiocytosis, non-Langerhans-cellSkin abnormalities
spellingShingle Sara Pires da Silva
Catarina Viveiros
Rui Almeida
Marta Almeida Pereira
Rute Vaz
Alexandrina Portela
JUVENILE XANTHOGRANULOMA: A CASE REPORT
Revista Paulista de Pediatria
Xanthogranuloma, juvenile
Histiocytosis, non-Langerhans-cell
Skin abnormalities
title JUVENILE XANTHOGRANULOMA: A CASE REPORT
title_full JUVENILE XANTHOGRANULOMA: A CASE REPORT
title_fullStr JUVENILE XANTHOGRANULOMA: A CASE REPORT
title_full_unstemmed JUVENILE XANTHOGRANULOMA: A CASE REPORT
title_short JUVENILE XANTHOGRANULOMA: A CASE REPORT
title_sort juvenile xanthogranuloma a case report
topic Xanthogranuloma, juvenile
Histiocytosis, non-Langerhans-cell
Skin abnormalities
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-05822019005004106&lng=en&tlng=en
work_keys_str_mv AT sarapiresdasilva juvenilexanthogranulomaacasereport
AT catarinaviveiros juvenilexanthogranulomaacasereport
AT ruialmeida juvenilexanthogranulomaacasereport
AT martaalmeidapereira juvenilexanthogranulomaacasereport
AT rutevaz juvenilexanthogranulomaacasereport
AT alexandrinaportela juvenilexanthogranulomaacasereport