Current Achievements and Applications of Transcriptomics in Personalized Cancer Medicine
Over the last decades, transcriptome profiling emerged as one of the most powerful approaches in oncology, providing prognostic and predictive utility for cancer management. The development of novel technologies, such as revolutionary next-generation sequencing, enables the identification of cancer...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-01-01
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| Series: | International Journal of Molecular Sciences |
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| Online Access: | https://www.mdpi.com/1422-0067/22/3/1422 |
| _version_ | 1797417446552895488 |
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| author | Stanislaw Supplitt Pawel Karpinski Maria Sasiadek Izabela Laczmanska |
| author_facet | Stanislaw Supplitt Pawel Karpinski Maria Sasiadek Izabela Laczmanska |
| author_sort | Stanislaw Supplitt |
| collection | DOAJ |
| description | Over the last decades, transcriptome profiling emerged as one of the most powerful approaches in oncology, providing prognostic and predictive utility for cancer management. The development of novel technologies, such as revolutionary next-generation sequencing, enables the identification of cancer biomarkers, gene signatures, and their aberrant expression affecting oncogenesis, as well as the discovery of molecular targets for anticancer therapies. Transcriptomics contribute to a change in the holistic understanding of cancer, from histopathological and organic to molecular classifications, opening a more personalized perspective for tumor diagnostics and therapy. The further advancement on transcriptome profiling may allow standardization and cost reduction of its analysis, which will be the next step for transcriptomics to become a canon of contemporary cancer medicine. |
| first_indexed | 2024-03-09T06:18:55Z |
| format | Article |
| id | doaj.art-8a98280d328e44659a28331e5343bdbb |
| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-09T06:18:55Z |
| publishDate | 2021-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-8a98280d328e44659a28331e5343bdbb2023-12-03T11:49:38ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672021-01-01223142210.3390/ijms22031422Current Achievements and Applications of Transcriptomics in Personalized Cancer MedicineStanislaw Supplitt0Pawel Karpinski1Maria Sasiadek2Izabela Laczmanska3Department of Genetics, Wroclaw Medical University, Marcinkowskiego 1, 50-368 Wroclaw, PolandDepartment of Genetics, Wroclaw Medical University, Marcinkowskiego 1, 50-368 Wroclaw, PolandDepartment of Genetics, Wroclaw Medical University, Marcinkowskiego 1, 50-368 Wroclaw, PolandDepartment of Genetics, Wroclaw Medical University, Marcinkowskiego 1, 50-368 Wroclaw, PolandOver the last decades, transcriptome profiling emerged as one of the most powerful approaches in oncology, providing prognostic and predictive utility for cancer management. The development of novel technologies, such as revolutionary next-generation sequencing, enables the identification of cancer biomarkers, gene signatures, and their aberrant expression affecting oncogenesis, as well as the discovery of molecular targets for anticancer therapies. Transcriptomics contribute to a change in the holistic understanding of cancer, from histopathological and organic to molecular classifications, opening a more personalized perspective for tumor diagnostics and therapy. The further advancement on transcriptome profiling may allow standardization and cost reduction of its analysis, which will be the next step for transcriptomics to become a canon of contemporary cancer medicine.https://www.mdpi.com/1422-0067/22/3/1422transcriptomicsRNAcanceroncogenesispersonalized medicine |
| spellingShingle | Stanislaw Supplitt Pawel Karpinski Maria Sasiadek Izabela Laczmanska Current Achievements and Applications of Transcriptomics in Personalized Cancer Medicine International Journal of Molecular Sciences transcriptomics RNA cancer oncogenesis personalized medicine |
| title | Current Achievements and Applications of Transcriptomics in Personalized Cancer Medicine |
| title_full | Current Achievements and Applications of Transcriptomics in Personalized Cancer Medicine |
| title_fullStr | Current Achievements and Applications of Transcriptomics in Personalized Cancer Medicine |
| title_full_unstemmed | Current Achievements and Applications of Transcriptomics in Personalized Cancer Medicine |
| title_short | Current Achievements and Applications of Transcriptomics in Personalized Cancer Medicine |
| title_sort | current achievements and applications of transcriptomics in personalized cancer medicine |
| topic | transcriptomics RNA cancer oncogenesis personalized medicine |
| url | https://www.mdpi.com/1422-0067/22/3/1422 |
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