Accelerating Onset of Puberty Through Modification of Early Life Nutrition Induces Modest but Persistent Changes in Bull Sperm DNA Methylation Profiles Post-puberty

Accelerating Onset of Puberty Through Modification of Early Life Nutrition Induces Modest but Persistent Changes in Bull Sperm DNA Methylation Profiles Post-puberty

In humans and model species, alterations of sperm DNA methylation patterns have been reported in cases of spermatogenesis defects, male infertility and exposure to toxins or nutritional challenges, suggesting that a memory of environmental or physiological changes is recorded in the sperm methylome....

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Bibliographic Details
Main Authors: Jean-Philippe Perrier, David A. Kenny, Aurélie Chaulot-Talmon, Colin J. Byrne, Eli Sellem, Luc Jouneau, Anne Aubert-Frambourg, Laurent Schibler, Hélène Jammes, Patrick Lonergan, Sean Fair, Hélène Kiefer
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Genetics
Subjects:
Bovine
puberty
spermatozoa
DNA methylation
nutritional programming
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2020.00945/full

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