Perinatal tissue-derived exosomes ameliorate colitis in mice by regulating the Foxp3 + Treg cells and gut microbiota

Perinatal tissue-derived exosomes ameliorate colitis in mice by regulating the Foxp3 + Treg cells and gut microbiota

Abstract Background The capacity of self-renewal and multipotent differentiation makes mesenchymal stem cells (MSC) one of the most widely investigated cell lines in preclinical studies as cell-based therapies. However, the low survival rate and poor homing efficiency of MSCs after transplantation h...

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Bibliographic Details
Main Authors: Yaping Yan, Kaixiu Li, Jiang Jiang, Lihong Jiang, Xiang Ma, Fang Ai, Shuai Qiu, Wei Si
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Stem Cell Research & Therapy
Subjects:
IBD
Exosomes
Foxp3 + Treg cells
Inflammatory
Gut microbiota
Online Access:https://doi.org/10.1186/s13287-023-03263-1

Internet

https://doi.org/10.1186/s13287-023-03263-1

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