Role of ADAM10 as a CD30 Sheddase in Classical Hodgkin Lymphoma

Role of ADAM10 as a CD30 Sheddase in Classical Hodgkin Lymphoma

Cancer cells generally recruit and influence non-malignant immune cells to support the tumor growth. Classical Hodgkin lymphoma (cHL) is a good example because the affected lymphoid tissue contains only a few malignant Hodgkin and Reed-Sternberg (H-RS) cells, which are supported by a massive infiltr...

Full description

Bibliographic Details
Main Authors: Hinrich P. Hansen, Adriana F. Paes Leme, Michael Hallek
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Immunology
Subjects:
Hodgkin lymphoma
CD30
ADAM10
antibody-drug conjugate
extracellular vesicle
cancer treatment
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00398/full

Similar Items

Similar Items