An Overview of Analytical Methods to Determine Pharmaceutical Active Compounds in Aquatic Organisms

There is increasing scientific evidence that some pharmaceuticals are present in the marine ecosystems at concentrations that may cause adverse effects on the organisms that inhabit them. At present, there is still very little scientific literature on the (bio)accumulation of these compounds in diff...

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Main Authors: María del Carmen Gómez-Regalado, Laura Martín-Pozo, Julia Martín, Juan Luis Santos, Irene Aparicio, Esteban Alonso, Alberto Zafra-Gómez
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/27/21/7569
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author María del Carmen Gómez-Regalado
Laura Martín-Pozo
Julia Martín
Juan Luis Santos
Irene Aparicio
Esteban Alonso
Alberto Zafra-Gómez
author_facet María del Carmen Gómez-Regalado
Laura Martín-Pozo
Julia Martín
Juan Luis Santos
Irene Aparicio
Esteban Alonso
Alberto Zafra-Gómez
author_sort María del Carmen Gómez-Regalado
collection DOAJ
description There is increasing scientific evidence that some pharmaceuticals are present in the marine ecosystems at concentrations that may cause adverse effects on the organisms that inhabit them. At present, there is still very little scientific literature on the (bio)accumulation of these compounds in different species, let alone on the relationship between the presence of these compounds and the adverse effects they produce. However, attempts have been made to optimize and validate analytical methods for the determination of residues of pharmaceuticals in marine biota by studying the stages of sample treatment, sample clean-up and subsequent analysis. The proposed bibliographic review includes a summary of the most commonly techniques, and its analytical features, proposed to determine pharmaceutical compounds in aquatic organisms at different levels of the trophic chain in the last 10 years.
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spelling doaj.art-8aa2cf013db243639ed268a9c6f6fd4a2023-11-24T06:06:36ZengMDPI AGMolecules1420-30492022-11-012721756910.3390/molecules27217569An Overview of Analytical Methods to Determine Pharmaceutical Active Compounds in Aquatic OrganismsMaría del Carmen Gómez-Regalado0Laura Martín-Pozo1Julia Martín2Juan Luis Santos3Irene Aparicio4Esteban Alonso5Alberto Zafra-Gómez6Department of Analytical Chemistry, Sciences Faculty, University of Granada, E-18071 Granada, SpainDepartment of Analytical Chemistry, Sciences Faculty, University of Granada, E-18071 Granada, SpainDepartamento de Química Analítica, Escuela Politécnica Superior, Universidad de Sevilla, C/Virgen de África 7, E-41011 Seville, SpainDepartamento de Química Analítica, Escuela Politécnica Superior, Universidad de Sevilla, C/Virgen de África 7, E-41011 Seville, SpainDepartamento de Química Analítica, Escuela Politécnica Superior, Universidad de Sevilla, C/Virgen de África 7, E-41011 Seville, SpainDepartamento de Química Analítica, Escuela Politécnica Superior, Universidad de Sevilla, C/Virgen de África 7, E-41011 Seville, SpainDepartment of Analytical Chemistry, Sciences Faculty, University of Granada, E-18071 Granada, SpainThere is increasing scientific evidence that some pharmaceuticals are present in the marine ecosystems at concentrations that may cause adverse effects on the organisms that inhabit them. At present, there is still very little scientific literature on the (bio)accumulation of these compounds in different species, let alone on the relationship between the presence of these compounds and the adverse effects they produce. However, attempts have been made to optimize and validate analytical methods for the determination of residues of pharmaceuticals in marine biota by studying the stages of sample treatment, sample clean-up and subsequent analysis. The proposed bibliographic review includes a summary of the most commonly techniques, and its analytical features, proposed to determine pharmaceutical compounds in aquatic organisms at different levels of the trophic chain in the last 10 years.https://www.mdpi.com/1420-3049/27/21/7569pharmaceuticalscontaminationanalytical methodsaquatic organismstrophic chain
spellingShingle María del Carmen Gómez-Regalado
Laura Martín-Pozo
Julia Martín
Juan Luis Santos
Irene Aparicio
Esteban Alonso
Alberto Zafra-Gómez
An Overview of Analytical Methods to Determine Pharmaceutical Active Compounds in Aquatic Organisms
Molecules
pharmaceuticals
contamination
analytical methods
aquatic organisms
trophic chain
title An Overview of Analytical Methods to Determine Pharmaceutical Active Compounds in Aquatic Organisms
title_full An Overview of Analytical Methods to Determine Pharmaceutical Active Compounds in Aquatic Organisms
title_fullStr An Overview of Analytical Methods to Determine Pharmaceutical Active Compounds in Aquatic Organisms
title_full_unstemmed An Overview of Analytical Methods to Determine Pharmaceutical Active Compounds in Aquatic Organisms
title_short An Overview of Analytical Methods to Determine Pharmaceutical Active Compounds in Aquatic Organisms
title_sort overview of analytical methods to determine pharmaceutical active compounds in aquatic organisms
topic pharmaceuticals
contamination
analytical methods
aquatic organisms
trophic chain
url https://www.mdpi.com/1420-3049/27/21/7569
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