Confidence interval based parameter estimation--a new SOCR applet and activity.

Many scientific investigations depend on obtaining data-driven, accurate, robust and computationally-tractable parameter estimates. In the face of unavoidable intrinsic variability, there are different algorithmic approaches, prior assumptions and fundamental principles for computing point and inter...

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मुख्य लेखकों: Nicolas Christou, Ivo D Dinov
स्वरूप: लेख
भाषा:English
प्रकाशित: Public Library of Science (PLoS) 2011-01-01
श्रृंखला:PLoS ONE
ऑनलाइन पहुंच:http://europepmc.org/articles/PMC3104980?pdf=render
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author Nicolas Christou
Ivo D Dinov
author_facet Nicolas Christou
Ivo D Dinov
author_sort Nicolas Christou
collection DOAJ
description Many scientific investigations depend on obtaining data-driven, accurate, robust and computationally-tractable parameter estimates. In the face of unavoidable intrinsic variability, there are different algorithmic approaches, prior assumptions and fundamental principles for computing point and interval estimates. Efficient and reliable parameter estimation is critical in making inference about observable experiments, summarizing process characteristics and prediction of experimental behaviors. In this manuscript, we demonstrate simulation, construction, validation and interpretation of confidence intervals, under various assumptions, using the interactive web-based tools provided by the Statistics Online Computational Resource (http://www.SOCR.ucla.edu). Specifically, we present confidence interval examples for population means, with known or unknown population standard deviation; population variance; population proportion (exact and approximate), as well as confidence intervals based on bootstrapping or the asymptotic properties of the maximum likelihood estimates. Like all SOCR resources, these confidence interval resources may be openly accessed via an Internet-connected Java-enabled browser. The SOCR confidence interval applet enables the user to empirically explore and investigate the effects of the confidence-level, the sample-size and parameter of interest on the corresponding confidence interval. Two applications of the new interval estimation computational library are presented. The first one is a simulation of confidence interval estimating the US unemployment rate and the second application demonstrates the computations of point and interval estimates of hippocampal surface complexity for Alzheimers disease patients, mild cognitive impairment subjects and asymptomatic controls.
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spelling doaj.art-8aa7f45f5d0e4e339f5c20f03e403e2c2022-12-22T03:43:46ZengPublic Library of Science (PLoS)PLoS ONE1932-62032011-01-0165e1917810.1371/journal.pone.0019178Confidence interval based parameter estimation--a new SOCR applet and activity.Nicolas ChristouIvo D DinovMany scientific investigations depend on obtaining data-driven, accurate, robust and computationally-tractable parameter estimates. In the face of unavoidable intrinsic variability, there are different algorithmic approaches, prior assumptions and fundamental principles for computing point and interval estimates. Efficient and reliable parameter estimation is critical in making inference about observable experiments, summarizing process characteristics and prediction of experimental behaviors. In this manuscript, we demonstrate simulation, construction, validation and interpretation of confidence intervals, under various assumptions, using the interactive web-based tools provided by the Statistics Online Computational Resource (http://www.SOCR.ucla.edu). Specifically, we present confidence interval examples for population means, with known or unknown population standard deviation; population variance; population proportion (exact and approximate), as well as confidence intervals based on bootstrapping or the asymptotic properties of the maximum likelihood estimates. Like all SOCR resources, these confidence interval resources may be openly accessed via an Internet-connected Java-enabled browser. The SOCR confidence interval applet enables the user to empirically explore and investigate the effects of the confidence-level, the sample-size and parameter of interest on the corresponding confidence interval. Two applications of the new interval estimation computational library are presented. The first one is a simulation of confidence interval estimating the US unemployment rate and the second application demonstrates the computations of point and interval estimates of hippocampal surface complexity for Alzheimers disease patients, mild cognitive impairment subjects and asymptomatic controls.http://europepmc.org/articles/PMC3104980?pdf=render
spellingShingle Nicolas Christou
Ivo D Dinov
Confidence interval based parameter estimation--a new SOCR applet and activity.
PLoS ONE
title Confidence interval based parameter estimation--a new SOCR applet and activity.
title_full Confidence interval based parameter estimation--a new SOCR applet and activity.
title_fullStr Confidence interval based parameter estimation--a new SOCR applet and activity.
title_full_unstemmed Confidence interval based parameter estimation--a new SOCR applet and activity.
title_short Confidence interval based parameter estimation--a new SOCR applet and activity.
title_sort confidence interval based parameter estimation a new socr applet and activity
url http://europepmc.org/articles/PMC3104980?pdf=render
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AT ivoddinov confidenceintervalbasedparameterestimationanewsocrappletandactivity