Anxiety-like behavior and anxiolytic treatment in the Rett syndrome natural history study

Anxiety-like behavior and anxiolytic treatment in the Rett syndrome natural history study

Abstract Background Rett syndrome (RTT) is a neurodevelopmental disorder most often related to a pathogenic variant in the X-linked MECP2 gene. Internalizing behaviors appear to be common, but standard methods of diagnosing anxiety are not readily applied in this population which typically has cogni...

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Bibliographic Details
Main Authors: Caroline B. Buchanan, Jennifer L. Stallworth, Aubin E. Joy, Rebekah E. Dixon, Alexandra E. Scott, Arthur A. Beisang, Timothy A. Benke, Daniel G. Glaze, Richard H. Haas, Peter T. Heydemann, Mary D. Jones, Jane B. Lane, David N. Lieberman, Eric D. Marsh, Jeffrey L. Neul, Sarika U. Peters, Robin C. Ryther, Steve A. Skinner, Shannon M. Standridge, Walter E. Kaufmann, Alan K. Percy
Format: Article
Language:English
Published: BMC 2022-05-01
Series:Journal of Neurodevelopmental Disorders
Subjects:
Rett syndrome
Natural history studies
Anxiety
Anti-anxiety agents
Methyl-CpG-binding protein 2
Online Access:https://doi.org/10.1186/s11689-022-09432-2

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