Toxicological Effects of Roundup<sup>®</sup> on <i>Drosophila melanogaster</i> Reproduction
Herbicide use has increased dramatically since 2001, particularly Roundup<sup>®</sup>. Effective in agricultural practice, Roundup<sup>®</sup> adversely affects non-target organisms, including reproductive and endocrine systems. We exposed fruit flies, <i>Drosophila mel...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-07-01
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| Series: | Toxics |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2305-6304/9/7/161 |
| _version_ | 1797525990751076352 |
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| author | Kelly Muller Karina Herrera Becky Talyn Erik Melchiorre |
| author_facet | Kelly Muller Karina Herrera Becky Talyn Erik Melchiorre |
| author_sort | Kelly Muller |
| collection | DOAJ |
| description | Herbicide use has increased dramatically since 2001, particularly Roundup<sup>®</sup>. Effective in agricultural practice, Roundup<sup>®</sup> adversely affects non-target organisms, including reproductive and endocrine systems. We exposed fruit flies, <i>Drosophila melanogaster</i>, to either Roundup<sup>®</sup> Ready to Use, containing pelargonic acid and glyphosate, or Roundup<sup>®</sup> Super Concentrate, that includes glyphosate and POEA, at sublethal concentrations. Both Roundup<sup>®</sup> formulations reduced ovary volume with fewer mature oocytes, most adversely at the highest concentration tested. Flies exposed within 2 h of eclosion were affected more than at 4 h, suggesting a critical period of increased ovarian sensitivity. These results support multi-species evidence that glyphosate-based herbicides interfere with normal development of the reproductive systems of non-target organisms. |
| first_indexed | 2024-03-10T09:20:54Z |
| format | Article |
| id | doaj.art-8ab2cc6a3be8472c837acf0d3f1333b4 |
| institution | Directory Open Access Journal |
| issn | 2305-6304 |
| language | English |
| last_indexed | 2024-03-10T09:20:54Z |
| publishDate | 2021-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Toxics |
| spelling | doaj.art-8ab2cc6a3be8472c837acf0d3f1333b42023-11-22T05:10:31ZengMDPI AGToxics2305-63042021-07-019716110.3390/toxics9070161Toxicological Effects of Roundup<sup>®</sup> on <i>Drosophila melanogaster</i> ReproductionKelly Muller0Karina Herrera1Becky Talyn2Erik Melchiorre3Department of Chemistry and Biochemistry, California State University, 5500 University Parkway, San Bernardino, CA 92407, USADepartment of Chemistry and Biochemistry, California State University, 5500 University Parkway, San Bernardino, CA 92407, USADepartment of Biology and College of Natural Sciences, California State University, 5500 University Parkway, San Bernardino, CA 92407, USADepartment of Geology, California State University, 5500 University Parkway, San Bernardino, CA 92407, USAHerbicide use has increased dramatically since 2001, particularly Roundup<sup>®</sup>. Effective in agricultural practice, Roundup<sup>®</sup> adversely affects non-target organisms, including reproductive and endocrine systems. We exposed fruit flies, <i>Drosophila melanogaster</i>, to either Roundup<sup>®</sup> Ready to Use, containing pelargonic acid and glyphosate, or Roundup<sup>®</sup> Super Concentrate, that includes glyphosate and POEA, at sublethal concentrations. Both Roundup<sup>®</sup> formulations reduced ovary volume with fewer mature oocytes, most adversely at the highest concentration tested. Flies exposed within 2 h of eclosion were affected more than at 4 h, suggesting a critical period of increased ovarian sensitivity. These results support multi-species evidence that glyphosate-based herbicides interfere with normal development of the reproductive systems of non-target organisms.https://www.mdpi.com/2305-6304/9/7/161Roundup<sup>®</sup>glyphosatepelargonic acid<i>Drosophila melanogaster</i>reproduction |
| spellingShingle | Kelly Muller Karina Herrera Becky Talyn Erik Melchiorre Toxicological Effects of Roundup<sup>®</sup> on <i>Drosophila melanogaster</i> Reproduction Toxics Roundup<sup>®</sup> glyphosate pelargonic acid <i>Drosophila melanogaster</i> reproduction |
| title | Toxicological Effects of Roundup<sup>®</sup> on <i>Drosophila melanogaster</i> Reproduction |
| title_full | Toxicological Effects of Roundup<sup>®</sup> on <i>Drosophila melanogaster</i> Reproduction |
| title_fullStr | Toxicological Effects of Roundup<sup>®</sup> on <i>Drosophila melanogaster</i> Reproduction |
| title_full_unstemmed | Toxicological Effects of Roundup<sup>®</sup> on <i>Drosophila melanogaster</i> Reproduction |
| title_short | Toxicological Effects of Roundup<sup>®</sup> on <i>Drosophila melanogaster</i> Reproduction |
| title_sort | toxicological effects of roundup sup r sup on i drosophila melanogaster i reproduction |
| topic | Roundup<sup>®</sup> glyphosate pelargonic acid <i>Drosophila melanogaster</i> reproduction |
| url | https://www.mdpi.com/2305-6304/9/7/161 |
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