Molecular Mechanism by Which Cobra Venom Cardiotoxins Interact with the Outer Mitochondrial Membrane

Molecular Mechanism by Which Cobra Venom Cardiotoxins Interact with the Outer Mitochondrial Membrane

Cardiotoxin CTII from <i>Naja oxiana</i> cobra venom translocates to the intermembrane space (IMS) of mitochondria to disrupt the structure and function of the inner mitochondrial membrane. At low concentrations, CTII facilitates ATP-synthase activity, presumably via the formation of non...

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Bibliographic Details
Main Authors:	Feng Li, Indira H. Shrivastava, Paul Hanlon, Ruben K. Dagda, Edward S. Gasanoff
Format:	Article
Language:	English
Published:	MDPI AG 2020-06-01
Series:	Toxins
Subjects:	cobra cardiotoxins non-bilayer immobilized phospholipids outer mitochondrial membrane cardiolipin phosphatidylcholine ATP-synthase
Online Access:	https://www.mdpi.com/2072-6651/12/7/425

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