Continuous renal replacement therapy attenuates polymorphonuclear myeloid-derived suppressor cell expansion in pediatric severe sepsis

Continuous renal replacement therapy attenuates polymorphonuclear myeloid-derived suppressor cell expansion in pediatric severe sepsis

BackgroundMyeloid-derived suppressor cells (MDSCs) expansion is an important mechanism underlying immunosuppression during sepsis. Though continuous renal replacement therapy (CRRT) may attenuate hyperinflammatory response in sepsis, its role in regulating MDSCs is unknown. The aim of this study was...

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Bibliographic Details
Main Authors: Shuyun Feng, Yun Cui, Yiping Zhou, Lujing Shao, Huijie Miao, Jiaying Dou, Tiantian Liu, Chunxia Wang, Yucai Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Immunology
Subjects:
pediatric intensive care units
myeloid-derived suppressor cells
continuous renal replacement therapy
sepsis
mortality
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.990522/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.990522/full

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