Wild-type Transthyretin Amyloid Deposition in an Ascending Aortic Aneurysm
Amyloid deposition in aortic tissue is associated with increased stiffness. We report a patient with ascending aortic aneurysm and chronic abdominal aortic dissection who had significant wild-type transthyretin amyloid deposition on surgical pathology. The patient did not have cardiac involvement on...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2024-05-01
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| Series: | JACC: Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666084924000937 |
| _version_ | 1797235474534760448 |
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| author | Abbas Hoteit, MD Faye Victoria C. Casimero, MD James R. Stone, MD, PhD Duke Cameron, MD Eric M. Isselbacher, MD, MSc Reza Seyedsadjadi, MD Hanna K. Gaggin, MD, MPH |
| author_facet | Abbas Hoteit, MD Faye Victoria C. Casimero, MD James R. Stone, MD, PhD Duke Cameron, MD Eric M. Isselbacher, MD, MSc Reza Seyedsadjadi, MD Hanna K. Gaggin, MD, MPH |
| author_sort | Abbas Hoteit, MD |
| collection | DOAJ |
| description | Amyloid deposition in aortic tissue is associated with increased stiffness. We report a patient with ascending aortic aneurysm and chronic abdominal aortic dissection who had significant wild-type transthyretin amyloid deposition on surgical pathology. The patient did not have cardiac involvement on further workup. |
| first_indexed | 2024-04-24T16:48:32Z |
| format | Article |
| id | doaj.art-8abca7d0a23f44d39323e721f2c056c5 |
| institution | Directory Open Access Journal |
| issn | 2666-0849 |
| language | English |
| last_indexed | 2024-04-24T16:48:32Z |
| publishDate | 2024-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | JACC: Case Reports |
| spelling | doaj.art-8abca7d0a23f44d39323e721f2c056c52024-03-29T05:51:09ZengElsevierJACC: Case Reports2666-08492024-05-01299102311Wild-type Transthyretin Amyloid Deposition in an Ascending Aortic AneurysmAbbas Hoteit, MD0Faye Victoria C. Casimero, MD1James R. Stone, MD, PhD2Duke Cameron, MD3Eric M. Isselbacher, MD, MSc4Reza Seyedsadjadi, MD5Hanna K. Gaggin, MD, MPH6Cardiology Division, Massachusetts General Hospital, Boston, Massachusetts, USADepartment of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USADepartment of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USADepartment of Cardiac Surgery, Massachusetts General Hospital, Boston, Massachusetts, USAThoracic Aortic Center and Heart Center, Massachusetts General Hospital, and Harvard Medical School, Boston, Massachusetts, USADepartment of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USACardiology Division, Massachusetts General Hospital, Boston, Massachusetts, USA; Harvard Medical School, Boston, Massachusetts, USA; Address for correspondence: Dr Hanna K. Gaggin, Cardiology Division, Massachusetts General Hospital, Yawkey 5B, 55 Fruit Street, Boston, Massachusetts 02114, USA.Amyloid deposition in aortic tissue is associated with increased stiffness. We report a patient with ascending aortic aneurysm and chronic abdominal aortic dissection who had significant wild-type transthyretin amyloid deposition on surgical pathology. The patient did not have cardiac involvement on further workup.http://www.sciencedirect.com/science/article/pii/S2666084924000937ascending aortic aneurysmtransthyretin amyloidosis |
| spellingShingle | Abbas Hoteit, MD Faye Victoria C. Casimero, MD James R. Stone, MD, PhD Duke Cameron, MD Eric M. Isselbacher, MD, MSc Reza Seyedsadjadi, MD Hanna K. Gaggin, MD, MPH Wild-type Transthyretin Amyloid Deposition in an Ascending Aortic Aneurysm JACC: Case Reports ascending aortic aneurysm transthyretin amyloidosis |
| title | Wild-type Transthyretin Amyloid Deposition in an Ascending Aortic Aneurysm |
| title_full | Wild-type Transthyretin Amyloid Deposition in an Ascending Aortic Aneurysm |
| title_fullStr | Wild-type Transthyretin Amyloid Deposition in an Ascending Aortic Aneurysm |
| title_full_unstemmed | Wild-type Transthyretin Amyloid Deposition in an Ascending Aortic Aneurysm |
| title_short | Wild-type Transthyretin Amyloid Deposition in an Ascending Aortic Aneurysm |
| title_sort | wild type transthyretin amyloid deposition in an ascending aortic aneurysm |
| topic | ascending aortic aneurysm transthyretin amyloidosis |
| url | http://www.sciencedirect.com/science/article/pii/S2666084924000937 |
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