Aberrations in Lipid Expression and Metabolism in Psoriasis

Psoriasis (PSO) is a common skin disease that affects about 1%–3% of the general population. It is a great medical, social and economic burden since PSO is associated with many comorbidities, of which the most common are cardiometabolic disorders. Psoriatic patients suffer more frequently from obesi...

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Main Authors: Julia Nowowiejska, Anna Baran, Iwona Flisiak
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/22/12/6561
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author Julia Nowowiejska
Anna Baran
Iwona Flisiak
author_facet Julia Nowowiejska
Anna Baran
Iwona Flisiak
author_sort Julia Nowowiejska
collection DOAJ
description Psoriasis (PSO) is a common skin disease that affects about 1%–3% of the general population. It is a great medical, social and economic burden since PSO is associated with many comorbidities, of which the most common are cardiometabolic disorders. Psoriatic patients suffer more frequently from obesity, dyslipidemia, atherosclerosis, and nonalcoholic fatty liver disease. Research shows that lipid expression and metabolism disorders are present more often in such patients. This review focuses on a variety of aberrations in lipids in the skin, blood, and adipose tissue in psoriatic patients and their multifactorial impact on the pathogenesis of psoriasis.
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spelling doaj.art-8ac42cd485044b4f9930f2cea0e862ae2023-11-22T00:44:22ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672021-06-012212656110.3390/ijms22126561Aberrations in Lipid Expression and Metabolism in PsoriasisJulia Nowowiejska0Anna Baran1Iwona Flisiak2Department of Dermatology and Venereology, Medical University of Bialystok, Zurawia 14 St, 15-540 Bialystok, PolandDepartment of Dermatology and Venereology, Medical University of Bialystok, Zurawia 14 St, 15-540 Bialystok, PolandDepartment of Dermatology and Venereology, Medical University of Bialystok, Zurawia 14 St, 15-540 Bialystok, PolandPsoriasis (PSO) is a common skin disease that affects about 1%–3% of the general population. It is a great medical, social and economic burden since PSO is associated with many comorbidities, of which the most common are cardiometabolic disorders. Psoriatic patients suffer more frequently from obesity, dyslipidemia, atherosclerosis, and nonalcoholic fatty liver disease. Research shows that lipid expression and metabolism disorders are present more often in such patients. This review focuses on a variety of aberrations in lipids in the skin, blood, and adipose tissue in psoriatic patients and their multifactorial impact on the pathogenesis of psoriasis.https://www.mdpi.com/1422-0067/22/12/6561psoriasislipidscholesteroltriglyceridesfatty acidslipoprotein
spellingShingle Julia Nowowiejska
Anna Baran
Iwona Flisiak
Aberrations in Lipid Expression and Metabolism in Psoriasis
International Journal of Molecular Sciences
psoriasis
lipids
cholesterol
triglycerides
fatty acids
lipoprotein
title Aberrations in Lipid Expression and Metabolism in Psoriasis
title_full Aberrations in Lipid Expression and Metabolism in Psoriasis
title_fullStr Aberrations in Lipid Expression and Metabolism in Psoriasis
title_full_unstemmed Aberrations in Lipid Expression and Metabolism in Psoriasis
title_short Aberrations in Lipid Expression and Metabolism in Psoriasis
title_sort aberrations in lipid expression and metabolism in psoriasis
topic psoriasis
lipids
cholesterol
triglycerides
fatty acids
lipoprotein
url https://www.mdpi.com/1422-0067/22/12/6561
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