Aberrations in Lipid Expression and Metabolism in Psoriasis
Psoriasis (PSO) is a common skin disease that affects about 1%–3% of the general population. It is a great medical, social and economic burden since PSO is associated with many comorbidities, of which the most common are cardiometabolic disorders. Psoriatic patients suffer more frequently from obesi...
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MDPI AG
2021-06-01
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Series: | International Journal of Molecular Sciences |
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Online Access: | https://www.mdpi.com/1422-0067/22/12/6561 |
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author | Julia Nowowiejska Anna Baran Iwona Flisiak |
author_facet | Julia Nowowiejska Anna Baran Iwona Flisiak |
author_sort | Julia Nowowiejska |
collection | DOAJ |
description | Psoriasis (PSO) is a common skin disease that affects about 1%–3% of the general population. It is a great medical, social and economic burden since PSO is associated with many comorbidities, of which the most common are cardiometabolic disorders. Psoriatic patients suffer more frequently from obesity, dyslipidemia, atherosclerosis, and nonalcoholic fatty liver disease. Research shows that lipid expression and metabolism disorders are present more often in such patients. This review focuses on a variety of aberrations in lipids in the skin, blood, and adipose tissue in psoriatic patients and their multifactorial impact on the pathogenesis of psoriasis. |
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format | Article |
id | doaj.art-8ac42cd485044b4f9930f2cea0e862ae |
institution | Directory Open Access Journal |
issn | 1661-6596 1422-0067 |
language | English |
last_indexed | 2024-03-10T10:17:43Z |
publishDate | 2021-06-01 |
publisher | MDPI AG |
record_format | Article |
series | International Journal of Molecular Sciences |
spelling | doaj.art-8ac42cd485044b4f9930f2cea0e862ae2023-11-22T00:44:22ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672021-06-012212656110.3390/ijms22126561Aberrations in Lipid Expression and Metabolism in PsoriasisJulia Nowowiejska0Anna Baran1Iwona Flisiak2Department of Dermatology and Venereology, Medical University of Bialystok, Zurawia 14 St, 15-540 Bialystok, PolandDepartment of Dermatology and Venereology, Medical University of Bialystok, Zurawia 14 St, 15-540 Bialystok, PolandDepartment of Dermatology and Venereology, Medical University of Bialystok, Zurawia 14 St, 15-540 Bialystok, PolandPsoriasis (PSO) is a common skin disease that affects about 1%–3% of the general population. It is a great medical, social and economic burden since PSO is associated with many comorbidities, of which the most common are cardiometabolic disorders. Psoriatic patients suffer more frequently from obesity, dyslipidemia, atherosclerosis, and nonalcoholic fatty liver disease. Research shows that lipid expression and metabolism disorders are present more often in such patients. This review focuses on a variety of aberrations in lipids in the skin, blood, and adipose tissue in psoriatic patients and their multifactorial impact on the pathogenesis of psoriasis.https://www.mdpi.com/1422-0067/22/12/6561psoriasislipidscholesteroltriglyceridesfatty acidslipoprotein |
spellingShingle | Julia Nowowiejska Anna Baran Iwona Flisiak Aberrations in Lipid Expression and Metabolism in Psoriasis International Journal of Molecular Sciences psoriasis lipids cholesterol triglycerides fatty acids lipoprotein |
title | Aberrations in Lipid Expression and Metabolism in Psoriasis |
title_full | Aberrations in Lipid Expression and Metabolism in Psoriasis |
title_fullStr | Aberrations in Lipid Expression and Metabolism in Psoriasis |
title_full_unstemmed | Aberrations in Lipid Expression and Metabolism in Psoriasis |
title_short | Aberrations in Lipid Expression and Metabolism in Psoriasis |
title_sort | aberrations in lipid expression and metabolism in psoriasis |
topic | psoriasis lipids cholesterol triglycerides fatty acids lipoprotein |
url | https://www.mdpi.com/1422-0067/22/12/6561 |
work_keys_str_mv | AT julianowowiejska aberrationsinlipidexpressionandmetabolisminpsoriasis AT annabaran aberrationsinlipidexpressionandmetabolisminpsoriasis AT iwonaflisiak aberrationsinlipidexpressionandmetabolisminpsoriasis |