Scaffold Searching of FDA and EMA-Approved Drugs Identifies Lead Candidates for Drug Repurposing in Alzheimer’s Disease

Scaffold Searching of FDA and EMA-Approved Drugs Identifies Lead Candidates for Drug Repurposing in Alzheimer’s Disease

Clinical trials of novel therapeutics for Alzheimer’s Disease (AD) have consumed a significant amount of time and resources with largely negative results. Repurposing drugs already approved by the Food and Drug Administration (FDA), European Medicines Agency (EMA), or Worldwide for another indicatio...

Bibliografske podrobnosti
Main Authors:	Sergey Shityakov, Ekaterina V. Skorb, Carola Y. Förster, Thomas Dandekar
Format:	Article
Jezik:	English
Izdano:	Frontiers Media S.A. 2021-10-01
Serija:	Frontiers in Chemistry
Teme:	scaffold search approved drugs drug repurposing alzheimer's disease chemical similarity molecular modeling
Online dostop:	https://www.frontiersin.org/articles/10.3389/fchem.2021.736509/full

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