Scaffold Searching of FDA and EMA-Approved Drugs Identifies Lead Candidates for Drug Repurposing in Alzheimer’s Disease

Scaffold Searching of FDA and EMA-Approved Drugs Identifies Lead Candidates for Drug Repurposing in Alzheimer’s Disease

Clinical trials of novel therapeutics for Alzheimer’s Disease (AD) have consumed a significant amount of time and resources with largely negative results. Repurposing drugs already approved by the Food and Drug Administration (FDA), European Medicines Agency (EMA), or Worldwide for another indicatio...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: Sergey Shityakov, Ekaterina V. Skorb, Carola Y. Förster, Thomas Dandekar
Format: Artykuł
Język:English
Wydane: Frontiers Media S.A. 2021-10-01
Seria:Frontiers in Chemistry
Hasła przedmiotowe:
scaffold search
approved drugs
drug repurposing
alzheimer's disease
chemical similarity
molecular modeling
Dostęp online:https://www.frontiersin.org/articles/10.3389/fchem.2021.736509/full

Internet

https://www.frontiersin.org/articles/10.3389/fchem.2021.736509/full

Podobne zapisy