Scaffold Searching of FDA and EMA-Approved Drugs Identifies Lead Candidates for Drug Repurposing in Alzheimer’s Disease

Clinical trials of novel therapeutics for Alzheimer’s Disease (AD) have consumed a significant amount of time and resources with largely negative results. Repurposing drugs already approved by the Food and Drug Administration (FDA), European Medicines Agency (EMA), or Worldwide for another indicatio...

Полное описание

Библиографические подробности
Главные авторы: Sergey Shityakov, Ekaterina V. Skorb, Carola Y. Förster, Thomas Dandekar
Формат: Статья
Язык:English
Опубликовано: Frontiers Media S.A. 2021-10-01
Серии:Frontiers in Chemistry
Предметы:
Online-ссылка:https://www.frontiersin.org/articles/10.3389/fchem.2021.736509/full