The Importance of Gender-Related Anticancer Research on Mitochondrial Regulator Sodium Dichloroacetate in Preclinical Studies In Vivo

The Importance of Gender-Related Anticancer Research on Mitochondrial Regulator Sodium Dichloroacetate in Preclinical Studies In Vivo

Sodium dichloroacetate (DCA) is an investigational medicinal product which has a potential anticancer preparation as a metabolic regulator in cancer cells’ mitochondria. Inhibition of pyruvate dehydrogenase kinases by DCA keeps the pyruvate dehydrogenase complex in the active form, resulti...

Full description

Bibliographic Details
Main Authors: Donatas Stakišaitis, Milda Juknevičienė, Eligija Damanskienė, Angelija Valančiūtė, Ingrida Balnytė, Marta Maria Alonso
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Cancers
Subjects:
sodium dichloroacetate
cancer
preclinical research
gender differences
Online Access:https://www.mdpi.com/2072-6694/11/8/1210

Similar Items

Similar Items