Vibration Measurement of Middle Ear Structure Using Doppler Optical Coherence Tomography: Preliminary Study
Objectives Doppler optical coherence tomography (DOCT) is useful for both, the spatially resolved measurement of the tympanic membrane (TM) oscillation and high-resolution imaging. We demonstrated a new technique capable of providing real-time two-dimensional Doppler OCT image of rapidly oscillatory...
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| Format: | Article |
| Language: | English |
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Korean Society of Otorhinolaryngology-Head and Neck Surgery
2019-02-01
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| Series: | Clinical and Experimental Otorhinolaryngology |
| Subjects: | |
| Online Access: | http://www.e-ceo.org/upload/pdf/ceo-2018-00185.pdf |
| _version_ | 1811215927797088256 |
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| author | Doekmin Jeon Nam Hyun Cho Kibeom Park Kanghae Kim Mansik Jeon Jeong Hun Jang Jeehyun Kim |
| author_facet | Doekmin Jeon Nam Hyun Cho Kibeom Park Kanghae Kim Mansik Jeon Jeong Hun Jang Jeehyun Kim |
| author_sort | Doekmin Jeon |
| collection | DOAJ |
| description | Objectives Doppler optical coherence tomography (DOCT) is useful for both, the spatially resolved measurement of the tympanic membrane (TM) oscillation and high-resolution imaging. We demonstrated a new technique capable of providing real-time two-dimensional Doppler OCT image of rapidly oscillatory latex mini-drum and in vivo rat TM and ossicles. Methods Using DOCT system, the oscillation of sample was measured at frequency range of 1–4 kHz at an output of 15 W. After the sensitivity of the DOCT system was verified using a latex mini-drum consisting of a 100 μm-thick latex membrane, changes in displacement of the umbo and contacted area between TM and malleus in normal and pathologic conditions. Results The oscillation cycles of the mini-drum for stimulus frequencies were 1.006 kHz for 1 kHz, 2.012 kHz for 2kHz, and 3.912 kHz for 4 kHz, which means that the oscillation cycle of the mini-drum become short in proportional to the frequency of stimuli. The oscillation cycles of umbo area and the junction area in normal TM for frequencies of the stimuli showed similar integer ratio with the data of latex mini-drum for stimuli less than 4 kHz. In the case of middle ear effusion condition, the Doppler signal showed a tendency of attenuation in all frequencies, which was prominent at 1 kHz and 2 kHz. Conclusion The TM vibration under sound stimulation with frequencies from 1 kHz to 4 kHz in normal and pathologic conditions was demonstrated using signal demodulation method in in vivo condition. The OCT technology could be helpful for functional and structural assessment as an optional modality. |
| first_indexed | 2024-04-12T06:31:34Z |
| format | Article |
| id | doaj.art-8ac89ee5d9f743f8bbca96a4d3d77847 |
| institution | Directory Open Access Journal |
| issn | 1976-8710 2005-0720 |
| language | English |
| last_indexed | 2024-04-12T06:31:34Z |
| publishDate | 2019-02-01 |
| publisher | Korean Society of Otorhinolaryngology-Head and Neck Surgery |
| record_format | Article |
| series | Clinical and Experimental Otorhinolaryngology |
| spelling | doaj.art-8ac89ee5d9f743f8bbca96a4d3d778472022-12-22T03:44:00ZengKorean Society of Otorhinolaryngology-Head and Neck SurgeryClinical and Experimental Otorhinolaryngology1976-87102005-07202019-02-01121404910.21053/ceo.2018.00185588Vibration Measurement of Middle Ear Structure Using Doppler Optical Coherence Tomography: Preliminary StudyDoekmin Jeon0Nam Hyun Cho1Kibeom Park2Kanghae Kim3Mansik Jeon4Jeong Hun Jang5Jeehyun Kim6 School of Electronics Engineering, College of IT Engineering, Kyungpook National University, Daegu, Korea Department of Otology and Laryngology, Harvard Medical School, Boston, MA, USA School of Electronics Engineering, College of IT Engineering, Kyungpook National University, Daegu, Korea School of Electronics Engineering, College of IT Engineering, Kyungpook National University, Daegu, Korea School of Electronics Engineering, College of IT Engineering, Kyungpook National University, Daegu, Korea Department of Otolaryngology, Ajou University School of Medicine, Suwon, Korea School of Electronics Engineering, College of IT Engineering, Kyungpook National University, Daegu, KoreaObjectives Doppler optical coherence tomography (DOCT) is useful for both, the spatially resolved measurement of the tympanic membrane (TM) oscillation and high-resolution imaging. We demonstrated a new technique capable of providing real-time two-dimensional Doppler OCT image of rapidly oscillatory latex mini-drum and in vivo rat TM and ossicles. Methods Using DOCT system, the oscillation of sample was measured at frequency range of 1–4 kHz at an output of 15 W. After the sensitivity of the DOCT system was verified using a latex mini-drum consisting of a 100 μm-thick latex membrane, changes in displacement of the umbo and contacted area between TM and malleus in normal and pathologic conditions. Results The oscillation cycles of the mini-drum for stimulus frequencies were 1.006 kHz for 1 kHz, 2.012 kHz for 2kHz, and 3.912 kHz for 4 kHz, which means that the oscillation cycle of the mini-drum become short in proportional to the frequency of stimuli. The oscillation cycles of umbo area and the junction area in normal TM for frequencies of the stimuli showed similar integer ratio with the data of latex mini-drum for stimuli less than 4 kHz. In the case of middle ear effusion condition, the Doppler signal showed a tendency of attenuation in all frequencies, which was prominent at 1 kHz and 2 kHz. Conclusion The TM vibration under sound stimulation with frequencies from 1 kHz to 4 kHz in normal and pathologic conditions was demonstrated using signal demodulation method in in vivo condition. The OCT technology could be helpful for functional and structural assessment as an optional modality.http://www.e-ceo.org/upload/pdf/ceo-2018-00185.pdfOptical Coherence TomographyDopplerMiddle EarTympanic Membrane |
| spellingShingle | Doekmin Jeon Nam Hyun Cho Kibeom Park Kanghae Kim Mansik Jeon Jeong Hun Jang Jeehyun Kim Vibration Measurement of Middle Ear Structure Using Doppler Optical Coherence Tomography: Preliminary Study Clinical and Experimental Otorhinolaryngology Optical Coherence Tomography Doppler Middle Ear Tympanic Membrane |
| title | Vibration Measurement of Middle Ear Structure Using Doppler Optical Coherence Tomography: Preliminary Study |
| title_full | Vibration Measurement of Middle Ear Structure Using Doppler Optical Coherence Tomography: Preliminary Study |
| title_fullStr | Vibration Measurement of Middle Ear Structure Using Doppler Optical Coherence Tomography: Preliminary Study |
| title_full_unstemmed | Vibration Measurement of Middle Ear Structure Using Doppler Optical Coherence Tomography: Preliminary Study |
| title_short | Vibration Measurement of Middle Ear Structure Using Doppler Optical Coherence Tomography: Preliminary Study |
| title_sort | vibration measurement of middle ear structure using doppler optical coherence tomography preliminary study |
| topic | Optical Coherence Tomography Doppler Middle Ear Tympanic Membrane |
| url | http://www.e-ceo.org/upload/pdf/ceo-2018-00185.pdf |
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