TTV and other anelloviruses: The astonishingly wide spread of a viral infection
The broad family of viruses known as anelloviruses (AV) infects both humans and numerous animal species. They have a tiny, covalently closed single-stranded DNA genome and the astonishing capacity to infect a very high percentage of healthy and ill people with chronic infections that could last a li...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-01-01
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| Series: | Aspects of Molecular Medicine |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2949688823000060 |
| _version_ | 1797237902984347648 |
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| author | Pietro Giorgio Spezia Daniele Focosi Andreina Baj Federica Novazzi Francesca Drago Ferrante Fabrizio Carletti Claudia Minosse Giulia Matusali Fabrizio Maggi |
| author_facet | Pietro Giorgio Spezia Daniele Focosi Andreina Baj Federica Novazzi Francesca Drago Ferrante Fabrizio Carletti Claudia Minosse Giulia Matusali Fabrizio Maggi |
| author_sort | Pietro Giorgio Spezia |
| collection | DOAJ |
| description | The broad family of viruses known as anelloviruses (AV) infects both humans and numerous animal species. They have a tiny, covalently closed single-stranded DNA genome and the astonishing capacity to infect a very high percentage of healthy and ill people with chronic infections that could last a lifetime. AV, and particularly the prototype Torquetenovirus, have established a successful interaction with the host's immune system and the rate at which they replicate is a gauge to measure overall immune function, even though many aspects of their life cycle and pathogenesis are still poorly understood. |
| first_indexed | 2024-04-24T17:27:08Z |
| format | Article |
| id | doaj.art-8ac98395896049f194c5c96618b94207 |
| institution | Directory Open Access Journal |
| issn | 2949-6888 |
| language | English |
| last_indexed | 2024-04-24T17:27:08Z |
| publishDate | 2023-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Aspects of Molecular Medicine |
| spelling | doaj.art-8ac98395896049f194c5c96618b942072024-03-28T06:39:48ZengElsevierAspects of Molecular Medicine2949-68882023-01-011100006TTV and other anelloviruses: The astonishingly wide spread of a viral infectionPietro Giorgio Spezia0Daniele Focosi1Andreina Baj2Federica Novazzi3Francesca Drago Ferrante4Fabrizio Carletti5Claudia Minosse6Giulia Matusali7Fabrizio Maggi8Department of Translational Research, University of Pisa, ItalyNorth-Western Tuscany Blood Bank, Pisa University Hospital, Pisa, ItalyDepartment of Medicine and Surgery, University of Insubria, Varese, ItalyDepartment of Medicine and Surgery, University of Insubria, Varese, ItalyDepartment of Medicine and Surgery, University of Insubria, Varese, ItalyLaboratory of Virology and Biosafety Laboratories, National Institute of Infectious Diseases “L. Spallanzani” IRCCS, Rome, ItalyLaboratory of Virology and Biosafety Laboratories, National Institute of Infectious Diseases “L. Spallanzani” IRCCS, Rome, ItalyLaboratory of Virology and Biosafety Laboratories, National Institute of Infectious Diseases “L. Spallanzani” IRCCS, Rome, ItalyLaboratory of Virology and Biosafety Laboratories, National Institute of Infectious Diseases “L. Spallanzani” IRCCS, Rome, Italy; Corresponding author. Laboratory of Virology and Biosafety Laboratories National Institute of Infectious Diseases “L. Spallanzani” Via Portuense 292, 00149, Rome, Italy.The broad family of viruses known as anelloviruses (AV) infects both humans and numerous animal species. They have a tiny, covalently closed single-stranded DNA genome and the astonishing capacity to infect a very high percentage of healthy and ill people with chronic infections that could last a lifetime. AV, and particularly the prototype Torquetenovirus, have established a successful interaction with the host's immune system and the rate at which they replicate is a gauge to measure overall immune function, even though many aspects of their life cycle and pathogenesis are still poorly understood.http://www.sciencedirect.com/science/article/pii/S2949688823000060TTVAnellovirusTTMVTTMDVViromeImmune system |
| spellingShingle | Pietro Giorgio Spezia Daniele Focosi Andreina Baj Federica Novazzi Francesca Drago Ferrante Fabrizio Carletti Claudia Minosse Giulia Matusali Fabrizio Maggi TTV and other anelloviruses: The astonishingly wide spread of a viral infection Aspects of Molecular Medicine TTV Anellovirus TTMV TTMDV Virome Immune system |
| title | TTV and other anelloviruses: The astonishingly wide spread of a viral infection |
| title_full | TTV and other anelloviruses: The astonishingly wide spread of a viral infection |
| title_fullStr | TTV and other anelloviruses: The astonishingly wide spread of a viral infection |
| title_full_unstemmed | TTV and other anelloviruses: The astonishingly wide spread of a viral infection |
| title_short | TTV and other anelloviruses: The astonishingly wide spread of a viral infection |
| title_sort | ttv and other anelloviruses the astonishingly wide spread of a viral infection |
| topic | TTV Anellovirus TTMV TTMDV Virome Immune system |
| url | http://www.sciencedirect.com/science/article/pii/S2949688823000060 |
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