Pulmonary Cavity: An Additional Entity to the Spectrum of COVID-19 Complications
The latest pandemic caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is known to manifest in various forms, ranging from a mild illness to a life-threatening condition. Though lung cavitation has not been commonly reported as a post Coronavirus Disease-2019 (COVID-19) infection...
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| Format: | Article |
| Language: | English |
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JCDR Research and Publications Private Limited
2022-07-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://www.jcdr.net/articles/PDF/16663/55252_CE_[Nik]_F(KR)_PF1(SC_SS)_PFA(SC_KM)_PN(KM).pdf |
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| author | Keertivardhan D Kulkarni V Pranavi Apoorva Ravi HT Lathadevi SM Biradar |
| author_facet | Keertivardhan D Kulkarni V Pranavi Apoorva Ravi HT Lathadevi SM Biradar |
| author_sort | Keertivardhan D Kulkarni |
| collection | DOAJ |
| description | The latest pandemic caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is known to manifest in various forms, ranging from a mild illness to a life-threatening condition. Though lung cavitation has not been commonly reported as a post Coronavirus Disease-2019 (COVID-19) infection complication, there has been a rise in the number of patients presenting with lung cavitation post the viral infection. In this case series, authors have reported four cases of lung cavitation developed post COVID-19 infection. Three out of four patients were newly diagnosed cases of diabetes, all received steroids as a part of treatment for COVID-19 infection. Three patients showed a temporary improvement in their condition after COVID-19 treatment, in the form of decreasing trends of inflammatory markers and decreased total count, but subsequently developed signs of super added infection during the course of their illness. Two patients had associated sino-orbital mucormycosis. Two patients required the support of non invasive ventilation and did not show clinical improvement, while one amongst the two succumbed to the infection. The cause for the development of lung cavities post COVID-19 infection is difficult to speculate it appears to be multifactorial with factors including isolated bacterial, fungal infections or bacterial and fungal co-infection, SARS-CoV-2 specific inflammatory pathways, and the immunosuppressive effects of glucocorticoids. |
| first_indexed | 2024-04-10T09:46:34Z |
| format | Article |
| id | doaj.art-8ac9d64823b941a69ff96d06029b3714 |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-04-10T09:46:34Z |
| publishDate | 2022-07-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-8ac9d64823b941a69ff96d06029b37142023-02-17T04:57:14ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2022-07-01167OR01OR0510.7860/JCDR/2022/55252.16663Pulmonary Cavity: An Additional Entity to the Spectrum of COVID-19 ComplicationsKeertivardhan D Kulkarni0V Pranavi1Apoorva Ravi2HT Lathadevi3SM Biradar4Associate Professor, Department of Respiratory Medicine, Shri. B. M. Patil Medical College, Hospital and Research Centre, Vijayapura, Karnataka, India.Postgraduate Student, Department of Respiratory Medicine, Shri. B. M. Patil Medical College, Hospital and Research Centre, Vijayapura, Karnataka, India.Postgraduate Student, Department of Respiratory Medicine, Shri. B. M. Patil Medical College, Hospital and Research Centre, Vijayapura, Karnataka, India.Professor, Department of Ear, Nose and Throat, Shri. B. M. Patil Medical College, Hospital and Research Centre, Vijayapura, Karnataka, India.Professor, Department of General Medicine, Shri. B. M. Patil Medical College, Hospital and Research Centre, Vijayapura, Karnataka, India.The latest pandemic caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is known to manifest in various forms, ranging from a mild illness to a life-threatening condition. Though lung cavitation has not been commonly reported as a post Coronavirus Disease-2019 (COVID-19) infection complication, there has been a rise in the number of patients presenting with lung cavitation post the viral infection. In this case series, authors have reported four cases of lung cavitation developed post COVID-19 infection. Three out of four patients were newly diagnosed cases of diabetes, all received steroids as a part of treatment for COVID-19 infection. Three patients showed a temporary improvement in their condition after COVID-19 treatment, in the form of decreasing trends of inflammatory markers and decreased total count, but subsequently developed signs of super added infection during the course of their illness. Two patients had associated sino-orbital mucormycosis. Two patients required the support of non invasive ventilation and did not show clinical improvement, while one amongst the two succumbed to the infection. The cause for the development of lung cavities post COVID-19 infection is difficult to speculate it appears to be multifactorial with factors including isolated bacterial, fungal infections or bacterial and fungal co-infection, SARS-CoV-2 specific inflammatory pathways, and the immunosuppressive effects of glucocorticoids.https://www.jcdr.net/articles/PDF/16663/55252_CE_[Nik]_F(KR)_PF1(SC_SS)_PFA(SC_KM)_PN(KM).pdfcoronavirus disease-2019co-infectionfungal infectionsmucormycosissteroids |
| spellingShingle | Keertivardhan D Kulkarni V Pranavi Apoorva Ravi HT Lathadevi SM Biradar Pulmonary Cavity: An Additional Entity to the Spectrum of COVID-19 Complications Journal of Clinical and Diagnostic Research coronavirus disease-2019 co-infection fungal infections mucormycosis steroids |
| title | Pulmonary Cavity: An Additional Entity to the Spectrum of COVID-19 Complications |
| title_full | Pulmonary Cavity: An Additional Entity to the Spectrum of COVID-19 Complications |
| title_fullStr | Pulmonary Cavity: An Additional Entity to the Spectrum of COVID-19 Complications |
| title_full_unstemmed | Pulmonary Cavity: An Additional Entity to the Spectrum of COVID-19 Complications |
| title_short | Pulmonary Cavity: An Additional Entity to the Spectrum of COVID-19 Complications |
| title_sort | pulmonary cavity an additional entity to the spectrum of covid 19 complications |
| topic | coronavirus disease-2019 co-infection fungal infections mucormycosis steroids |
| url | https://www.jcdr.net/articles/PDF/16663/55252_CE_[Nik]_F(KR)_PF1(SC_SS)_PFA(SC_KM)_PN(KM).pdf |
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