The first case of gland inclusion in an intrapulmonary lymph node: a mimic of metastasis
Abstract Background Lymph node inclusions are foci of ectopic tissue in lymph nodes, which were reported in different areas of the body. However, inclusions in the mediastinal lymph node are rare. Here, we report the first case of glandular inclusion within the parenchyma of the intrapulmonary lymph...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2019-11-01
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| Series: | World Journal of Surgical Oncology |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12957-019-1726-1 |
| _version_ | 1818256181981872128 |
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| author | Chenglong Wang Yijia Cao Min Zeng Lijuan Wang Xiaojing Cao Lingfeng Zou Youde Cao |
| author_facet | Chenglong Wang Yijia Cao Min Zeng Lijuan Wang Xiaojing Cao Lingfeng Zou Youde Cao |
| author_sort | Chenglong Wang |
| collection | DOAJ |
| description | Abstract Background Lymph node inclusions are foci of ectopic tissue in lymph nodes, which were reported in different areas of the body. However, inclusions in the mediastinal lymph node are rare. Here, we report the first case of glandular inclusion within the parenchyma of the intrapulmonary lymph node in a patient with primary lung adenocarcinoma. Case presentation A computed tomography (CT) scan showed a solid pulmonary nodule in the right upper lobe in a 44-year-old man. After a fine needle aspiration biopsy diagnosis of adenocarcinoma, lobectomy and lymph dissection were performed. Histological sections of the lung demonstrated a papillary predominant adenocarcinoma and one intrapulmonary lymph node, which displayed glandular inclusion occupying the node parenchyma. The gland inclusion was very similar to metastasis, but was formed by two layers of epithelial cells, and the abluminal cells were positive for P63, P40, and CK5/6. The patient has remained alive without recurrence and metastasis at the last follow-up before publication. Conclusions It is very important to correctly diagnose a lymph node inclusion for proper clinical management. |
| first_indexed | 2024-12-12T17:23:41Z |
| format | Article |
| id | doaj.art-8aca62aac4604be1b4da3ea599a5a0e7 |
| institution | Directory Open Access Journal |
| issn | 1477-7819 |
| language | English |
| last_indexed | 2024-12-12T17:23:41Z |
| publishDate | 2019-11-01 |
| publisher | BMC |
| record_format | Article |
| series | World Journal of Surgical Oncology |
| spelling | doaj.art-8aca62aac4604be1b4da3ea599a5a0e72022-12-22T00:17:34ZengBMCWorld Journal of Surgical Oncology1477-78192019-11-011711410.1186/s12957-019-1726-1The first case of gland inclusion in an intrapulmonary lymph node: a mimic of metastasisChenglong Wang0Yijia Cao1Min Zeng2Lijuan Wang3Xiaojing Cao4Lingfeng Zou5Youde Cao6Department of Pathology, Chongqing Hospital of Traditional Chinese MedicineDepartment of Pathology, Chongqing Hospital of Traditional Chinese MedicineDepartment of Pathology, Chongqing Hospital of Traditional Chinese MedicineDepartment of Pathology, Chongqing Hospital of Traditional Chinese MedicineDepartment of Pathology, Chongqing Hospital of Traditional Chinese MedicineDepartment of Pathology, Chongqing Hospital of Traditional Chinese MedicineDepartment of Pathology, Chongqing Hospital of Traditional Chinese MedicineAbstract Background Lymph node inclusions are foci of ectopic tissue in lymph nodes, which were reported in different areas of the body. However, inclusions in the mediastinal lymph node are rare. Here, we report the first case of glandular inclusion within the parenchyma of the intrapulmonary lymph node in a patient with primary lung adenocarcinoma. Case presentation A computed tomography (CT) scan showed a solid pulmonary nodule in the right upper lobe in a 44-year-old man. After a fine needle aspiration biopsy diagnosis of adenocarcinoma, lobectomy and lymph dissection were performed. Histological sections of the lung demonstrated a papillary predominant adenocarcinoma and one intrapulmonary lymph node, which displayed glandular inclusion occupying the node parenchyma. The gland inclusion was very similar to metastasis, but was formed by two layers of epithelial cells, and the abluminal cells were positive for P63, P40, and CK5/6. The patient has remained alive without recurrence and metastasis at the last follow-up before publication. Conclusions It is very important to correctly diagnose a lymph node inclusion for proper clinical management.http://link.springer.com/article/10.1186/s12957-019-1726-1Lung adenocarcinomaMetastasisEpithelial inclusionLymph nodeTumour staging |
| spellingShingle | Chenglong Wang Yijia Cao Min Zeng Lijuan Wang Xiaojing Cao Lingfeng Zou Youde Cao The first case of gland inclusion in an intrapulmonary lymph node: a mimic of metastasis World Journal of Surgical Oncology Lung adenocarcinoma Metastasis Epithelial inclusion Lymph node Tumour staging |
| title | The first case of gland inclusion in an intrapulmonary lymph node: a mimic of metastasis |
| title_full | The first case of gland inclusion in an intrapulmonary lymph node: a mimic of metastasis |
| title_fullStr | The first case of gland inclusion in an intrapulmonary lymph node: a mimic of metastasis |
| title_full_unstemmed | The first case of gland inclusion in an intrapulmonary lymph node: a mimic of metastasis |
| title_short | The first case of gland inclusion in an intrapulmonary lymph node: a mimic of metastasis |
| title_sort | first case of gland inclusion in an intrapulmonary lymph node a mimic of metastasis |
| topic | Lung adenocarcinoma Metastasis Epithelial inclusion Lymph node Tumour staging |
| url | http://link.springer.com/article/10.1186/s12957-019-1726-1 |
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