Differential Methylation of Telomere-Related Genes Is Associated with Kidney Disease in Individuals with Type 1 Diabetes

Differential Methylation of Telomere-Related Genes Is Associated with Kidney Disease in Individuals with Type 1 Diabetes

Diabetic kidney disease (DKD) represents a major global health problem. Accelerated ageing is a key feature of DKD and, therefore, characteristics of accelerated ageing may provide useful biomarkers or therapeutic targets. Harnessing multi-omics, features affecting telomere biology and any associate...

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Bibliographic Details
Main Authors: Claire Hill, Seamus Duffy, Laura M. Kettyle, Liane McGlynn, Niina Sandholm, Rany M. Salem, Alex Thompson, Elizabeth J. Swan, Jill Kilner, Peter Rossing, Paul G. Shiels, Maria Lajer, Per-Henrik Groop, Alexander Peter Maxwell, Amy Jayne McKnight, on behalf of the GENIE Consortium
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Genes
Subjects:
biological ageing
diabetic kidney disease
epigenetic
genetic
methylation
SNP
Online Access:https://www.mdpi.com/2073-4425/14/5/1029

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