Explorative study on the use of omalizumab in patients suffering from interstitial cystitis/bladder pain syndrome
The aim of this study was to evaluate the efficacy of omalizumab in the treatment of Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS), evaluated by visual analogue score for pain and urgency- frequency, O’Leary-Sant IC symptom and problem index questionnaire, Pain Urgency Frequency questionnaire...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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PAGEPress Publications
2012-06-01
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| Series: | Urogynaecologia International Journal |
| Subjects: | |
| Online Access: | http://www.urogynaecologia.org/index.php/uij/article/view/112 |
| _version_ | 1811344640042860544 |
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| author | Daniele Porru Enrica Bucchioni Marcello Macchi Fabio Leva Alberto Parmigiani Davide Barletta Dimitrios Choussos Barbara Gardella Maria Diletta Daccò Rossella Elena Nappi Massimo Allegri Carlo Maria Bianchi Arsenio Spinillo Bruno Rovereto |
| author_facet | Daniele Porru Enrica Bucchioni Marcello Macchi Fabio Leva Alberto Parmigiani Davide Barletta Dimitrios Choussos Barbara Gardella Maria Diletta Daccò Rossella Elena Nappi Massimo Allegri Carlo Maria Bianchi Arsenio Spinillo Bruno Rovereto |
| author_sort | Daniele Porru |
| collection | DOAJ |
| description | The aim of this study was to evaluate the efficacy of omalizumab in the treatment of Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS), evaluated by visual analogue score for pain and urgency- frequency, O’Leary-Sant IC symptom and problem index questionnaire, Pain Urgency Frequency questionnaire and Patient Global Assessment questionnaire. Four female patients with a diagnosis of IC/BPS were included in the study, with an age between 20 and 39 years. In the first patient the subjective final evaluation was of a marked improvement. The second patient had a moderate improvement of the subjective final evaluation. The third patient considered her overall clinical situation to have slightly improved after treatment. One 32-year-old patient, with multiple allergies, discontinued treatment after 3 months and could not complete the study due to side effects. Omalizumab was subcutaneously administered to patients with IC/PBS; it induced both a subjective and objective improvement of symptoms in 2 patients enrolled in the study. |
| first_indexed | 2024-04-13T19:51:11Z |
| format | Article |
| id | doaj.art-8aceede7357c475aa3019cad87c51b5b |
| institution | Directory Open Access Journal |
| issn | 1121-3086 2038-8314 |
| language | English |
| last_indexed | 2024-04-13T19:51:11Z |
| publishDate | 2012-06-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Urogynaecologia International Journal |
| spelling | doaj.art-8aceede7357c475aa3019cad87c51b5b2022-12-22T02:32:32ZengPAGEPress PublicationsUrogynaecologia International Journal1121-30862038-83142012-06-0126110.4081/uij.2012.e8Explorative study on the use of omalizumab in patients suffering from interstitial cystitis/bladder pain syndromeDaniele Porru0Enrica Bucchioni1Marcello Macchi2Fabio Leva3Alberto Parmigiani4Davide Barletta5Dimitrios Choussos6Barbara Gardella7Maria Diletta Daccò8Rossella Elena Nappi9Massimo Allegri10Carlo Maria Bianchi11Arsenio Spinillo12Bruno Rovereto13Urology Department, IRCCS San Matteo Hospital, PaviaNovartis Italia, Origgio (VA)Urology Department, IRCCS San Matteo Hospital, PaviaUrology Department, IRCCS San Matteo Hospital, PaviaUrology Department, IRCCS San Matteo Hospital, PaviaUrology Department, IRCCS San Matteo Hospital, PaviaUrology Department, IRCCS San Matteo Hospital, PaviaObstetric and Gynecology Clinics IRCCS San Matteo Hospital, PaviaObstetric and Gynecology Clinics IRCCS San Matteo Hospital, PaviaObstetric and Gynecology Clinics IRCCS San Matteo Hospital, PaviaPain Therapy Service Fondazione IRCCS Policlinico San Matteo, Department of Resuscitation and Organ Transplantation surgery sciences, Section of Anesthesiology and Resuscitation, University of PaviaSchool of Specialization in Urology, University of Pavia,Obstetric and Gynecology Clinics IRCCS San Matteo Hospital, PaviaUrology Department, IRCCS San Matteo Hospital, Pavia,The aim of this study was to evaluate the efficacy of omalizumab in the treatment of Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS), evaluated by visual analogue score for pain and urgency- frequency, O’Leary-Sant IC symptom and problem index questionnaire, Pain Urgency Frequency questionnaire and Patient Global Assessment questionnaire. Four female patients with a diagnosis of IC/BPS were included in the study, with an age between 20 and 39 years. In the first patient the subjective final evaluation was of a marked improvement. The second patient had a moderate improvement of the subjective final evaluation. The third patient considered her overall clinical situation to have slightly improved after treatment. One 32-year-old patient, with multiple allergies, discontinued treatment after 3 months and could not complete the study due to side effects. Omalizumab was subcutaneously administered to patients with IC/PBS; it induced both a subjective and objective improvement of symptoms in 2 patients enrolled in the study.http://www.urogynaecologia.org/index.php/uij/article/view/112anti-IgE treatmentinterstitial cystitis/ bladder pain syndromeomalizumab. |
| spellingShingle | Daniele Porru Enrica Bucchioni Marcello Macchi Fabio Leva Alberto Parmigiani Davide Barletta Dimitrios Choussos Barbara Gardella Maria Diletta Daccò Rossella Elena Nappi Massimo Allegri Carlo Maria Bianchi Arsenio Spinillo Bruno Rovereto Explorative study on the use of omalizumab in patients suffering from interstitial cystitis/bladder pain syndrome Urogynaecologia International Journal anti-IgE treatment interstitial cystitis/ bladder pain syndrome omalizumab. |
| title | Explorative study on the use of omalizumab in patients suffering from interstitial cystitis/bladder pain syndrome |
| title_full | Explorative study on the use of omalizumab in patients suffering from interstitial cystitis/bladder pain syndrome |
| title_fullStr | Explorative study on the use of omalizumab in patients suffering from interstitial cystitis/bladder pain syndrome |
| title_full_unstemmed | Explorative study on the use of omalizumab in patients suffering from interstitial cystitis/bladder pain syndrome |
| title_short | Explorative study on the use of omalizumab in patients suffering from interstitial cystitis/bladder pain syndrome |
| title_sort | explorative study on the use of omalizumab in patients suffering from interstitial cystitis bladder pain syndrome |
| topic | anti-IgE treatment interstitial cystitis/ bladder pain syndrome omalizumab. |
| url | http://www.urogynaecologia.org/index.php/uij/article/view/112 |
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