Preparation of polymeric vesicles with tertiary amine and epoxy functional groups via polymerization-induced self-assembly
Polymeric vesicles with tertiary amine and epoxy functional groups were fabricated via the reversible addition-fragmentation chain transfer (RAFT) dispersion polymerization of 2-(diisopropylamino) ethyl methacrylate (DIPEMA) and glycidyl methacrylate (GlyMA) in an ethanol-water mixture by using poly...
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| Format: | Article |
| Language: | English |
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EDP Sciences
2023-01-01
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| Series: | E3S Web of Conferences |
| Subjects: | |
| Online Access: | https://www.e3s-conferences.org/articles/e3sconf/pdf/2023/12/e3sconf_esat2023_01002.pdf |
| _version_ | 1797850848401817600 |
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| author | Zhang Fen Yao Qian Li Yantao Niu Yanling Chen Xiaoqi Zhou Haijun |
| author_facet | Zhang Fen Yao Qian Li Yantao Niu Yanling Chen Xiaoqi Zhou Haijun |
| author_sort | Zhang Fen |
| collection | DOAJ |
| description | Polymeric vesicles with tertiary amine and epoxy functional groups were fabricated via the reversible addition-fragmentation chain transfer (RAFT) dispersion polymerization of 2-(diisopropylamino) ethyl methacrylate (DIPEMA) and glycidyl methacrylate (GlyMA) in an ethanol-water mixture by using poly (ethylene oxide)-4-(4-Cyanopentanoic acid) dithiobenzoate (mPEG45-CPADB) as the macro-chain-transfer agent (macro-CTA). Biocompatible polymer mPEG45 with molecular weight of 2000 and 4-(4-Cyanopentanoic acid) dithiobenzoate (CPADB) were used for the macro-CTA synthesizing via the esterification reaction. Investigation of the degree of polymerization (DP) of the hydrophobic block P(DIPEMA-co-GlyMA) and the solid content indicated that both have significant effect on the particle morphology and particle diameter. 1H NMR and FTIR analysis indicated the existing of tertiary amine and epoxy functional groups on the produced vesicles. |
| first_indexed | 2024-04-09T19:08:12Z |
| format | Article |
| id | doaj.art-8ad21f2aa7bb40eaa663e7f66bfc0947 |
| institution | Directory Open Access Journal |
| issn | 2267-1242 |
| language | English |
| last_indexed | 2024-04-09T19:08:12Z |
| publishDate | 2023-01-01 |
| publisher | EDP Sciences |
| record_format | Article |
| series | E3S Web of Conferences |
| spelling | doaj.art-8ad21f2aa7bb40eaa663e7f66bfc09472023-04-07T08:56:58ZengEDP SciencesE3S Web of Conferences2267-12422023-01-013750100210.1051/e3sconf/202337501002e3sconf_esat2023_01002Preparation of polymeric vesicles with tertiary amine and epoxy functional groups via polymerization-induced self-assemblyZhang Fen0Yao Qian1Li Yantao2Niu Yanling3Chen Xiaoqi4Zhou Haijun5Institute of Energy Resources, Hebei Academy of SciencesInstitute of Energy Resources, Hebei Academy of SciencesInstitute of Energy Resources, Hebei Academy of SciencesInstitute of Energy Resources, Hebei Academy of SciencesInstitute of Energy Resources, Hebei Academy of SciencesInstitute of Energy Resources, Hebei Academy of SciencesPolymeric vesicles with tertiary amine and epoxy functional groups were fabricated via the reversible addition-fragmentation chain transfer (RAFT) dispersion polymerization of 2-(diisopropylamino) ethyl methacrylate (DIPEMA) and glycidyl methacrylate (GlyMA) in an ethanol-water mixture by using poly (ethylene oxide)-4-(4-Cyanopentanoic acid) dithiobenzoate (mPEG45-CPADB) as the macro-chain-transfer agent (macro-CTA). Biocompatible polymer mPEG45 with molecular weight of 2000 and 4-(4-Cyanopentanoic acid) dithiobenzoate (CPADB) were used for the macro-CTA synthesizing via the esterification reaction. Investigation of the degree of polymerization (DP) of the hydrophobic block P(DIPEMA-co-GlyMA) and the solid content indicated that both have significant effect on the particle morphology and particle diameter. 1H NMR and FTIR analysis indicated the existing of tertiary amine and epoxy functional groups on the produced vesicles.https://www.e3s-conferences.org/articles/e3sconf/pdf/2023/12/e3sconf_esat2023_01002.pdfpolymeric vesiclespolymerization-induced self-assemblyreversible addition-fragmentation chain transferdispersion polymerization |
| spellingShingle | Zhang Fen Yao Qian Li Yantao Niu Yanling Chen Xiaoqi Zhou Haijun Preparation of polymeric vesicles with tertiary amine and epoxy functional groups via polymerization-induced self-assembly E3S Web of Conferences polymeric vesicles polymerization-induced self-assembly reversible addition-fragmentation chain transfer dispersion polymerization |
| title | Preparation of polymeric vesicles with tertiary amine and epoxy functional groups via polymerization-induced self-assembly |
| title_full | Preparation of polymeric vesicles with tertiary amine and epoxy functional groups via polymerization-induced self-assembly |
| title_fullStr | Preparation of polymeric vesicles with tertiary amine and epoxy functional groups via polymerization-induced self-assembly |
| title_full_unstemmed | Preparation of polymeric vesicles with tertiary amine and epoxy functional groups via polymerization-induced self-assembly |
| title_short | Preparation of polymeric vesicles with tertiary amine and epoxy functional groups via polymerization-induced self-assembly |
| title_sort | preparation of polymeric vesicles with tertiary amine and epoxy functional groups via polymerization induced self assembly |
| topic | polymeric vesicles polymerization-induced self-assembly reversible addition-fragmentation chain transfer dispersion polymerization |
| url | https://www.e3s-conferences.org/articles/e3sconf/pdf/2023/12/e3sconf_esat2023_01002.pdf |
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