N 6 -methyladenosine regulates glycolysis of cancer cells through PDK4

N 6 -methyladenosine regulates glycolysis of cancer cells through PDK4

Dysregulation of N6-Methyladenosine (m6A) is associated with cancer progression. Here, authors show that m6A methylation of pyruvate dehydrogenase kinase 4 (PDK4) positively regulates its mRNA stability and translation, and consequently affects glycolysis in cancer cells

Bibliographic Details
Main Authors:	Zihan Li, Yanxi Peng, Jiexin Li, Zhuojia Chen, Feng Chen, Jian Tu, Shuibin Lin, Hongsheng Wang
Format:	Article
Language:	English
Published:	Nature Portfolio 2020-05-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-020-16306-5

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