Effects of Ketamine on Neuronal Spontaneous Excitatory Postsynaptic Currents and Miniature Excitatory Postsynaptic Currents in the Somatosensory Cortex of Rats

Effects of Ketamine on Neuronal Spontaneous Excitatory Postsynaptic Currents and Miniature Excitatory Postsynaptic Currents in the Somatosensory Cortex of Rats

Background: Ketamine is a commonly used intravenous anesthetic which produces dissociation anesthesia, analgesia, and amnesia. The mechanism of ketamine-induced synaptic inhibition in high-level cortical areas is still unknown. We aimed to elucidate the effects of different concentrations of ketamin...

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Bibliographic Details
Main Authors: Chengdong Yuan, Yajun Zhang, Yu Zhang, Song Cao, Yuan Wang, Bao Fu, Tian Yu
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2016-07-01
Series:Iranian Journal of Medical Sciences
Subjects:
Ketamine
Patch-clamp techniques
Excitatory postsynaptic potentials
Synaptic transmission
Online Access:http://ijms.sums.ac.ir/index.php/IJMS/article/view/2533

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