Computational model of the full-length TSH receptor

Computational model of the full-length TSH receptor

(GPCR)The receptor for TSH receptor (TSHR), a G protein coupled receptor (GPCR), is of particular interest as the primary antigen in autoimmune hyperthyroidism (Graves’ disease) caused by stimulating TSHR antibodies. To date, only one domain of the extracellular region of the TSHR has been crystalli...

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Bibliographic Details
Main Authors: Mihaly Mezei, Rauf Latif, Terry F Davies
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-10-01
Series:eLife
Subjects:
TSHR
transmembrane domain
molecular dynamics
hinge region
linker region
TSH
Online Access:https://elifesciences.org/articles/81415

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