Pityriasis Versicolor Resistant to Antifungal Drugs in a Patient in Lomé (Togo)

Background. Pityriasis versicolor (PV) is a ubiquitous superficial skin mycosis that often affects young adults. It is often effectively treated with local or oral antifungal agents. Cases of PV resistance to antifungal agents have been reported rarely. We report a case of antifungal resistant PV. O...

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Main Authors: Julienne Teclessou, Koussake Kombate, Bayaki Saka, Séfako Abla Akakpo, Palokinam Pitche
Format: Article
Language:English
Published: Hindawi Limited 2022-01-01
Series:Case Reports in Dermatological Medicine
Online Access:http://dx.doi.org/10.1155/2022/5404913
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author Julienne Teclessou
Koussake Kombate
Bayaki Saka
Séfako Abla Akakpo
Palokinam Pitche
author_facet Julienne Teclessou
Koussake Kombate
Bayaki Saka
Séfako Abla Akakpo
Palokinam Pitche
author_sort Julienne Teclessou
collection DOAJ
description Background. Pityriasis versicolor (PV) is a ubiquitous superficial skin mycosis that often affects young adults. It is often effectively treated with local or oral antifungal agents. Cases of PV resistance to antifungal agents have been reported rarely. We report a case of antifungal resistant PV. Observation. A 22-year-old patient was followed since the age of 17 years in a dermatology outpatient clinic for hyperpigmented scaly macular lesions of the trunk and upper limbs. The clinical diagnosis of PV was retained. The patient was treated by fluconazole 300 mg/week before being lost to follow-up. He was seen again in 2019 (about 2 years later) for the same symptomatology and treated again by fluconazole and ciclopirox olamine cream without improvement. He was again lost to follow-up and seen again six months later. A mycological sample was taken and Aspergillus niger was isolated. The patient was treated by itraconazole for 6 weeks. The evolution was marked by a clinical status quo. The patient was again put on salicylated petroleum jelly 10% associated with terbinafine cream and then lost to follow-up. Conclusion. The emergence of fungal resistance to antifungal drugs does not spare PV. It can therefore be resistant to several antifungal drugs, leaving clinicians and patients in despair.
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spelling doaj.art-8ade58c842e14187a28c4ff849dbac772022-12-22T04:04:42ZengHindawi LimitedCase Reports in Dermatological Medicine2090-64712022-01-01202210.1155/2022/5404913Pityriasis Versicolor Resistant to Antifungal Drugs in a Patient in Lomé (Togo)Julienne Teclessou0Koussake Kombate1Bayaki Saka2Séfako Abla Akakpo3Palokinam Pitche4Department ofDepartment ofDepartment of Dermatology and STDsDepartment of Dermatology and STDsDepartment of Dermatology and STDsBackground. Pityriasis versicolor (PV) is a ubiquitous superficial skin mycosis that often affects young adults. It is often effectively treated with local or oral antifungal agents. Cases of PV resistance to antifungal agents have been reported rarely. We report a case of antifungal resistant PV. Observation. A 22-year-old patient was followed since the age of 17 years in a dermatology outpatient clinic for hyperpigmented scaly macular lesions of the trunk and upper limbs. The clinical diagnosis of PV was retained. The patient was treated by fluconazole 300 mg/week before being lost to follow-up. He was seen again in 2019 (about 2 years later) for the same symptomatology and treated again by fluconazole and ciclopirox olamine cream without improvement. He was again lost to follow-up and seen again six months later. A mycological sample was taken and Aspergillus niger was isolated. The patient was treated by itraconazole for 6 weeks. The evolution was marked by a clinical status quo. The patient was again put on salicylated petroleum jelly 10% associated with terbinafine cream and then lost to follow-up. Conclusion. The emergence of fungal resistance to antifungal drugs does not spare PV. It can therefore be resistant to several antifungal drugs, leaving clinicians and patients in despair.http://dx.doi.org/10.1155/2022/5404913
spellingShingle Julienne Teclessou
Koussake Kombate
Bayaki Saka
Séfako Abla Akakpo
Palokinam Pitche
Pityriasis Versicolor Resistant to Antifungal Drugs in a Patient in Lomé (Togo)
Case Reports in Dermatological Medicine
title Pityriasis Versicolor Resistant to Antifungal Drugs in a Patient in Lomé (Togo)
title_full Pityriasis Versicolor Resistant to Antifungal Drugs in a Patient in Lomé (Togo)
title_fullStr Pityriasis Versicolor Resistant to Antifungal Drugs in a Patient in Lomé (Togo)
title_full_unstemmed Pityriasis Versicolor Resistant to Antifungal Drugs in a Patient in Lomé (Togo)
title_short Pityriasis Versicolor Resistant to Antifungal Drugs in a Patient in Lomé (Togo)
title_sort pityriasis versicolor resistant to antifungal drugs in a patient in lome togo
url http://dx.doi.org/10.1155/2022/5404913
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AT bayakisaka pityriasisversicolorresistanttoantifungaldrugsinapatientinlometogo
AT sefakoablaakakpo pityriasisversicolorresistanttoantifungaldrugsinapatientinlometogo
AT palokinampitche pityriasisversicolorresistanttoantifungaldrugsinapatientinlometogo