Pencegahan hipertensi dan penebalan dinding aorta dengan pemberian kecambah kacang hijau (Phaseolus radiatus (L)) pada tikus putih Sprague Dawley
Background: Lifestyle changes with high-fat food consumption is one of the factors the risks of cardiovascular diseases like of coronary heart disease and atherosclerosis. A healthy diet and a balanced diet and consume foods that contain lots of antioxidants is one of the effective ways to prevent h...
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| Format: | Article |
| Language: | Indonesian |
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Universitas Gadjah Mada
2016-01-01
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| Series: | Jurnal Gizi Klinik Indonesia |
| Subjects: | |
| Online Access: | https://jurnal.ugm.ac.id/jgki/article/view/22454 |
| _version_ | 1818853076192198656 |
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| author | Novian Swasono Hadi Arta Farmawati Ahmad Ghozali |
| author_facet | Novian Swasono Hadi Arta Farmawati Ahmad Ghozali |
| author_sort | Novian Swasono Hadi |
| collection | DOAJ |
| description | Background: Lifestyle changes with high-fat food consumption is one of the factors the risks of cardiovascular diseases like of coronary heart disease and atherosclerosis. A healthy diet and a balanced diet and consume foods that contain lots of antioxidants is one of the effective ways to prevent hyperlipidemia. Mung bean sprouts have properties that neutralize free radicals cause Hyperlipidemia and cardiovascular diseases because it is an antioxidant compound.
Objective: The aim of this study was to determinate the effect of mung bean sprouts (Phaseolus radiatus (L)) to blood pressure and histopathology aorta of Sprague-Dawley male rats.
Method: The type of study was experimental research using pre-post test controlled group design for blood pressure variable and post test only controlled group design histopathology aorta. The thirty-five of Sprague-Dawley male rats was eight weeks divided into 5 groups. The first group was given standard diet, group 2 was given a hight fat diet, the third group was given a high-fat diet and mung bean sprout 0,67 gram, group 4 was given a high-fat diet and mung bean 1,34 gram, and group 5 was given a high-fat diet and vitamin E doses of 23 IU.
Results: Result of this study showed that after 4 weeks of treatment, increased in blood pressure systole in the given of high fat diet higher than group who were given a high fat diet and mung bean sprout and also on group who were given high fat diet and vitamin E, but there is no difference effect a decrease in blood pressure between the provision of mung bean sprouts and vitamin E (p>0,05). Statistical analysis to thick the wall the aorta show the similarity meaningful in all the treatment group, it can be said that overall thick the wall the aorta in this research is not different.
Conclusion: A dose of mung bean sprout 0,67 g is optimal doses in preventing a rise in blood pressure and prevent alterations histopathology Sprague-Dawley male rats. |
| first_indexed | 2024-12-19T07:31:04Z |
| format | Article |
| id | doaj.art-8ae174e14eac47b3aed9deec1555239e |
| institution | Directory Open Access Journal |
| issn | 1693-900X 2502-4140 |
| language | Indonesian |
| last_indexed | 2024-12-19T07:31:04Z |
| publishDate | 2016-01-01 |
| publisher | Universitas Gadjah Mada |
| record_format | Article |
| series | Jurnal Gizi Klinik Indonesia |
| spelling | doaj.art-8ae174e14eac47b3aed9deec1555239e2022-12-21T20:30:43ZindUniversitas Gadjah MadaJurnal Gizi Klinik Indonesia1693-900X2502-41402016-01-0112311612210.22146/ijcn.2245415732Pencegahan hipertensi dan penebalan dinding aorta dengan pemberian kecambah kacang hijau (Phaseolus radiatus (L)) pada tikus putih Sprague DawleyNovian Swasono Hadi0Arta Farmawati1Ahmad Ghozali2Jurusan Gizi Politeknik Kesehatan Kementerian Kesehatan GorontaloDepartemen Biokimia, Fakultas Kedokteran Universitas Gadjah MadaDepartemen Patologi Anatomi, Fakultas Kedokteran Universitas Gadjah MadaBackground: Lifestyle changes with high-fat food consumption is one of the factors the risks of cardiovascular diseases like of coronary heart disease and atherosclerosis. A healthy diet and a balanced diet and consume foods that contain lots of antioxidants is one of the effective ways to prevent hyperlipidemia. Mung bean sprouts have properties that neutralize free radicals cause Hyperlipidemia and cardiovascular diseases because it is an antioxidant compound. Objective: The aim of this study was to determinate the effect of mung bean sprouts (Phaseolus radiatus (L)) to blood pressure and histopathology aorta of Sprague-Dawley male rats. Method: The type of study was experimental research using pre-post test controlled group design for blood pressure variable and post test only controlled group design histopathology aorta. The thirty-five of Sprague-Dawley male rats was eight weeks divided into 5 groups. The first group was given standard diet, group 2 was given a hight fat diet, the third group was given a high-fat diet and mung bean sprout 0,67 gram, group 4 was given a high-fat diet and mung bean 1,34 gram, and group 5 was given a high-fat diet and vitamin E doses of 23 IU. Results: Result of this study showed that after 4 weeks of treatment, increased in blood pressure systole in the given of high fat diet higher than group who were given a high fat diet and mung bean sprout and also on group who were given high fat diet and vitamin E, but there is no difference effect a decrease in blood pressure between the provision of mung bean sprouts and vitamin E (p>0,05). Statistical analysis to thick the wall the aorta show the similarity meaningful in all the treatment group, it can be said that overall thick the wall the aorta in this research is not different. Conclusion: A dose of mung bean sprout 0,67 g is optimal doses in preventing a rise in blood pressure and prevent alterations histopathology Sprague-Dawley male rats.https://jurnal.ugm.ac.id/jgki/article/view/22454blood pressurehigh fat diethistopatology aortamung bean sprouts |
| spellingShingle | Novian Swasono Hadi Arta Farmawati Ahmad Ghozali Pencegahan hipertensi dan penebalan dinding aorta dengan pemberian kecambah kacang hijau (Phaseolus radiatus (L)) pada tikus putih Sprague Dawley Jurnal Gizi Klinik Indonesia blood pressure high fat diet histopatology aorta mung bean sprouts |
| title | Pencegahan hipertensi dan penebalan dinding aorta dengan pemberian kecambah kacang hijau (Phaseolus radiatus (L)) pada tikus putih Sprague Dawley |
| title_full | Pencegahan hipertensi dan penebalan dinding aorta dengan pemberian kecambah kacang hijau (Phaseolus radiatus (L)) pada tikus putih Sprague Dawley |
| title_fullStr | Pencegahan hipertensi dan penebalan dinding aorta dengan pemberian kecambah kacang hijau (Phaseolus radiatus (L)) pada tikus putih Sprague Dawley |
| title_full_unstemmed | Pencegahan hipertensi dan penebalan dinding aorta dengan pemberian kecambah kacang hijau (Phaseolus radiatus (L)) pada tikus putih Sprague Dawley |
| title_short | Pencegahan hipertensi dan penebalan dinding aorta dengan pemberian kecambah kacang hijau (Phaseolus radiatus (L)) pada tikus putih Sprague Dawley |
| title_sort | pencegahan hipertensi dan penebalan dinding aorta dengan pemberian kecambah kacang hijau phaseolus radiatus l pada tikus putih sprague dawley |
| topic | blood pressure high fat diet histopatology aorta mung bean sprouts |
| url | https://jurnal.ugm.ac.id/jgki/article/view/22454 |
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