Diagnostic Value of Preoperative uPAR-PET/CT in Regional Lymph Node Staging of Oral and Oropharyngeal Squamous Cell Carcinoma: A Prospective Phase II Trial
The detection of lymph node metastases is a major challenge in oral and oropharyngeal squamous cell carcinoma (OSCC and OPSCC). <sup>68</sup>Ga-NOTA-AE105 is a novel positron emission tomography (PET) radioligand with high affinity to urokinase-type plasminogen activator receptor (uPAR),...
Main Authors: | Mads Lawaetz, Anders Christensen, Karina Juhl, Giedrius Lelkaitis, Kirstine Karnov, Esben Andreas Carlsen, Birgitte W. Charabi, Annika Loft, Dorota Czyzewska, Christian von Buchwald, Andreas Kjaer |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-10-01
|
Series: | Diagnostics |
Subjects: | |
Online Access: | https://www.mdpi.com/2075-4418/13/21/3303 |
Similar Items
-
Potential of uPAR, αvβ6 Integrin, and Tissue Factor as Targets for Molecular Imaging of Oral Squamous Cell Carcinoma: Evaluation of Nine Targets in Primary Tumors and Metastases by Immunohistochemistry
by: Mads Lawaetz, et al.
Published: (2023-02-01) -
UPAR Overexpression Could Be a Potential Favorable Prognostic Marker in Invasive Ductal Carcinoma of Breast
by: Ata Abbasi, et al.
Published: (2022-06-01) -
uPAR PET/CT for Prognostication and Response Assessment in Patients with Metastatic Castration-Resistant Prostate Cancer Undergoing Radium-223 Therapy: A Prospective Phase II Study
by: Marie Øbro Fosbøl, et al.
Published: (2021-06-01) -
Cleavage of the urokinase receptor (uPAR) on oral cancer cells: regulation by transforming growth factor – β1 (TGF-β1) and potential effects on migration and invasion
by: Synnove Norvoll Magnussen, et al.
Published: (2017-05-01) -
The Urokinase Receptor (uPAR) as a “Trojan Horse” in Targeted Cancer Therapy: Challenges and Opportunities
by: Virginia Metrangolo, et al.
Published: (2021-10-01)