Occurrence and Fate of Antibiotics as Trace Contaminants in Wastewaters, Sewage Sludges, and Surface Waters

Environmental analytical studies show that trace concentrations of antibacterial agents (antibiotics) occur in hospital and municipal wastewaters and in the aquatic environment. Fluoroquinolones and macrolides, two important human-use antibiotic classes, were studied in detail. The results...

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Main Authors: Walter Giger, Alfredo C. Alder, Eva M. Golet, Hans-Peter E. Kohler, Christa S. McArdell, Eva Molnar, Hansrudolf Siegrist, Marc J.-F. Suter
Format: Article
Language:deu
Published: Swiss Chemical Society 2003-09-01
Series:CHIMIA
Subjects:
Online Access:https://chimia.ch/chimia/article/view/3727
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author Walter Giger
Alfredo C. Alder
Eva M. Golet
Hans-Peter E. Kohler
Christa S. McArdell
Eva Molnar
Hansrudolf Siegrist
Marc J.-F. Suter
author_facet Walter Giger
Alfredo C. Alder
Eva M. Golet
Hans-Peter E. Kohler
Christa S. McArdell
Eva Molnar
Hansrudolf Siegrist
Marc J.-F. Suter
author_sort Walter Giger
collection DOAJ
description Environmental analytical studies show that trace concentrations of antibacterial agents (antibiotics) occur in hospital and municipal wastewaters and in the aquatic environment. Fluoroquinolones and macrolides, two important human-use antibiotic classes, were studied in detail. The results are discussed regarding input sources and behavior in wastewater treatment and rivers. The fluoroquinolones ciprofloxacin and norfloxacin are substantially eliminated in wastewater treatment (80–90%) by sorption transfer to sewage sludge. In digested sludges the fluoroquinolones occur at mg/kg levels. Ciprofloxacin and norfloxacin are further removed in the Glatt river by 66 and 48%, respectively. The most abundant macrolide clarithromycin was detected at 57 to 330 ng/l concentrations in treated wastewater effluents. Different compositions of the macrolides (clarithromycin and erythromycin-H2O) determined in treated effluents of three wastewater treatment plants can be explained by distinct consumption patterns, in one case due to an international airport located in the catchment area. Residual levels of clarithromycin in the Glatt river were up to 75 ng/l with no apparent removal in the river. These results provide important information on environmental exposures, which can be incorporated into environmental risk assessments of the particular chemicals.
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spelling doaj.art-8ae4b6b2bded46819704003b5a567a312022-12-22T02:46:01ZdeuSwiss Chemical SocietyCHIMIA0009-42932673-24242003-09-0157910.2533/000942903777679064Occurrence and Fate of Antibiotics as Trace Contaminants in Wastewaters, Sewage Sludges, and Surface WatersWalter GigerAlfredo C. AlderEva M. GoletHans-Peter E. KohlerChrista S. McArdellEva MolnarHansrudolf SiegristMarc J.-F. Suter Environmental analytical studies show that trace concentrations of antibacterial agents (antibiotics) occur in hospital and municipal wastewaters and in the aquatic environment. Fluoroquinolones and macrolides, two important human-use antibiotic classes, were studied in detail. The results are discussed regarding input sources and behavior in wastewater treatment and rivers. The fluoroquinolones ciprofloxacin and norfloxacin are substantially eliminated in wastewater treatment (80–90%) by sorption transfer to sewage sludge. In digested sludges the fluoroquinolones occur at mg/kg levels. Ciprofloxacin and norfloxacin are further removed in the Glatt river by 66 and 48%, respectively. The most abundant macrolide clarithromycin was detected at 57 to 330 ng/l concentrations in treated wastewater effluents. Different compositions of the macrolides (clarithromycin and erythromycin-H2O) determined in treated effluents of three wastewater treatment plants can be explained by distinct consumption patterns, in one case due to an international airport located in the catchment area. Residual levels of clarithromycin in the Glatt river were up to 75 ng/l with no apparent removal in the river. These results provide important information on environmental exposures, which can be incorporated into environmental risk assessments of the particular chemicals. https://chimia.ch/chimia/article/view/3727CiprofloxacinClarithromycinFluoroquinolonesMacrolidesNorfloxacin
spellingShingle Walter Giger
Alfredo C. Alder
Eva M. Golet
Hans-Peter E. Kohler
Christa S. McArdell
Eva Molnar
Hansrudolf Siegrist
Marc J.-F. Suter
Occurrence and Fate of Antibiotics as Trace Contaminants in Wastewaters, Sewage Sludges, and Surface Waters
CHIMIA
Ciprofloxacin
Clarithromycin
Fluoroquinolones
Macrolides
Norfloxacin
title Occurrence and Fate of Antibiotics as Trace Contaminants in Wastewaters, Sewage Sludges, and Surface Waters
title_full Occurrence and Fate of Antibiotics as Trace Contaminants in Wastewaters, Sewage Sludges, and Surface Waters
title_fullStr Occurrence and Fate of Antibiotics as Trace Contaminants in Wastewaters, Sewage Sludges, and Surface Waters
title_full_unstemmed Occurrence and Fate of Antibiotics as Trace Contaminants in Wastewaters, Sewage Sludges, and Surface Waters
title_short Occurrence and Fate of Antibiotics as Trace Contaminants in Wastewaters, Sewage Sludges, and Surface Waters
title_sort occurrence and fate of antibiotics as trace contaminants in wastewaters sewage sludges and surface waters
topic Ciprofloxacin
Clarithromycin
Fluoroquinolones
Macrolides
Norfloxacin
url https://chimia.ch/chimia/article/view/3727
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