Inhibition of NOX2 or NLRP3 inflammasome prevents cardiac remote ischemic preconditioning

Inhibition of NOX2 or NLRP3 inflammasome prevents cardiac remote ischemic preconditioning

Introduction: Short episodes of ischemia-reperfusion (IR) in the heart (classical ischemic preconditioning, IPC) or in a limb (remote ischemic preconditioning, RIPC) before a prolonged ischemic episode, reduce the size of the infarct. It is unknown whether IPC and RIPC share common mechanisms of pro...

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Bibliographic Details
Main Authors: Sandra Benavides, Rodrigo Palavecino, Jaime A. Riquelme, Luis Montecinos, José Pablo Finkelstein, Paulina Donoso, Gina Sánchez
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Physiology
Subjects:
NOX2
NLRP3 inflammasome
heart
ischemia-reperfusion
infarct size
remote ischemic preconditioning
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2023.1327402/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2023.1327402/full

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