High-Resolution Computed Tomography: Lights and Shadows in Improving Care for SSc-ILD Patients
The diagnosis and classification of systemic sclerosis-associated interstitial lung disease (SSc-ILD) is essential to improve the prognosis of systemic sclerosis (SSc) patients. The risk-stratification of disease severity and follow-up requires a multidisciplinary approach, integrating high-resoluti...
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MDPI AG
2021-10-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/11/11/1960 |
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| author | Barbara Ruaro Elisa Baratella Paola Confalonieri Barbara Wade Cristina Marrocchio Pietro Geri Annalisa Busca Riccardo Pozzan Alessia Giovanna Andrisano Maria Assunta Cova Marco Confalonieri Francesco Salton |
| author_facet | Barbara Ruaro Elisa Baratella Paola Confalonieri Barbara Wade Cristina Marrocchio Pietro Geri Annalisa Busca Riccardo Pozzan Alessia Giovanna Andrisano Maria Assunta Cova Marco Confalonieri Francesco Salton |
| author_sort | Barbara Ruaro |
| collection | DOAJ |
| description | The diagnosis and classification of systemic sclerosis-associated interstitial lung disease (SSc-ILD) is essential to improve the prognosis of systemic sclerosis (SSc) patients. The risk-stratification of disease severity and follow-up requires a multidisciplinary approach, integrating high-resolution computed tomography (HRTC) of the lung, pulmonary function tests (PFT), along with clinical and symptomatic evaluations. The use of HRCT in detecting SSc-ILD is not so much based on a definitive validation, but rather reflects the widespread clinician recognition of dissatisfaction with other modalities. However, due to the heterogeneity of SSc-ILD and the potential absence of symptoms in early or mild disease, it is prudent to consider as many parameters as possible in the assessment and monitoring of newly diagnosed patients. An early diagnosis meets the primary goal, i.e., the prevention of disease progression. The current first line treatment regimens are mainly centered on immunosuppressive therapy. This review assesses the role HRCT plays in optimizing care and improving clinical outcomes in SSc-ILD patients. |
| first_indexed | 2024-03-10T05:34:36Z |
| format | Article |
| id | doaj.art-8aeb5174020449afb6dd3529d3502e55 |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-10T05:34:36Z |
| publishDate | 2021-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-8aeb5174020449afb6dd3529d3502e552023-11-22T23:00:19ZengMDPI AGDiagnostics2075-44182021-10-011111196010.3390/diagnostics11111960High-Resolution Computed Tomography: Lights and Shadows in Improving Care for SSc-ILD PatientsBarbara Ruaro0Elisa Baratella1Paola Confalonieri2Barbara Wade3Cristina Marrocchio4Pietro Geri5Annalisa Busca6Riccardo Pozzan7Alessia Giovanna Andrisano8Maria Assunta Cova9Marco Confalonieri10Francesco Salton11Department of Pulmonology, University Hospital of Cattinara, 34149 Trieste, ItalyDepartment of Radiology, Cattinara Hospital, University of Trieste, 34149 Trieste, ItalyDepartment of Pulmonology, University Hospital of Cattinara, 34149 Trieste, ItalyAOU City of Health and Science of Turin, Department of Science of Public Health and Pediatrics, University of Torino, 10124 Torino, ItalyDepartment of Radiology, Cattinara Hospital, University of Trieste, 34149 Trieste, ItalyDepartment of Pulmonology, University Hospital of Cattinara, 34149 Trieste, ItalyDepartment of Pulmonology, University Hospital of Cattinara, 34149 Trieste, ItalyDepartment of Pulmonology, University Hospital of Cattinara, 34149 Trieste, ItalyDepartment of Pulmonology, University Hospital of Cattinara, 34149 Trieste, ItalyDepartment of Radiology, Cattinara Hospital, University of Trieste, 34149 Trieste, ItalyDepartment of Pulmonology, University Hospital of Cattinara, 34149 Trieste, ItalyDepartment of Pulmonology, University Hospital of Cattinara, 34149 Trieste, ItalyThe diagnosis and classification of systemic sclerosis-associated interstitial lung disease (SSc-ILD) is essential to improve the prognosis of systemic sclerosis (SSc) patients. The risk-stratification of disease severity and follow-up requires a multidisciplinary approach, integrating high-resolution computed tomography (HRTC) of the lung, pulmonary function tests (PFT), along with clinical and symptomatic evaluations. The use of HRCT in detecting SSc-ILD is not so much based on a definitive validation, but rather reflects the widespread clinician recognition of dissatisfaction with other modalities. However, due to the heterogeneity of SSc-ILD and the potential absence of symptoms in early or mild disease, it is prudent to consider as many parameters as possible in the assessment and monitoring of newly diagnosed patients. An early diagnosis meets the primary goal, i.e., the prevention of disease progression. The current first line treatment regimens are mainly centered on immunosuppressive therapy. This review assesses the role HRCT plays in optimizing care and improving clinical outcomes in SSc-ILD patients.https://www.mdpi.com/2075-4418/11/11/1960systemic sclerosis-associated interstitial lung disease (SSc-ILD)interstitial lung disease (ILD)systemic sclerosis (SSc)high-resolution computed tomography (HRTC)pulmonary function tests (PFT)usual interstitial pneumonia (UIP) |
| spellingShingle | Barbara Ruaro Elisa Baratella Paola Confalonieri Barbara Wade Cristina Marrocchio Pietro Geri Annalisa Busca Riccardo Pozzan Alessia Giovanna Andrisano Maria Assunta Cova Marco Confalonieri Francesco Salton High-Resolution Computed Tomography: Lights and Shadows in Improving Care for SSc-ILD Patients Diagnostics systemic sclerosis-associated interstitial lung disease (SSc-ILD) interstitial lung disease (ILD) systemic sclerosis (SSc) high-resolution computed tomography (HRTC) pulmonary function tests (PFT) usual interstitial pneumonia (UIP) |
| title | High-Resolution Computed Tomography: Lights and Shadows in Improving Care for SSc-ILD Patients |
| title_full | High-Resolution Computed Tomography: Lights and Shadows in Improving Care for SSc-ILD Patients |
| title_fullStr | High-Resolution Computed Tomography: Lights and Shadows in Improving Care for SSc-ILD Patients |
| title_full_unstemmed | High-Resolution Computed Tomography: Lights and Shadows in Improving Care for SSc-ILD Patients |
| title_short | High-Resolution Computed Tomography: Lights and Shadows in Improving Care for SSc-ILD Patients |
| title_sort | high resolution computed tomography lights and shadows in improving care for ssc ild patients |
| topic | systemic sclerosis-associated interstitial lung disease (SSc-ILD) interstitial lung disease (ILD) systemic sclerosis (SSc) high-resolution computed tomography (HRTC) pulmonary function tests (PFT) usual interstitial pneumonia (UIP) |
| url | https://www.mdpi.com/2075-4418/11/11/1960 |
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