Unravelling the Therapeutic Potential of Antibiotics in Hypoxia in a Breast Cancer MCF-7 Cell Line Model

Unravelling the Therapeutic Potential of Antibiotics in Hypoxia in a Breast Cancer MCF-7 Cell Line Model

Antibiotics inhibit breast cancer stem cells (CSCs) by suppressing mitochondrial biogenesis. However, the effectiveness of antibiotics in clinical settings is inconsistent. This inconsistency raises the question of whether the tumor microenvironment, particularly hypoxia, plays a role in the respons...

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Bibliographic Details
Main Authors: Almaz A. Akhunzianov, Alfiya I. Nesterova, Sjoerd Wanrooij, Yulia V. Filina, Albert A. Rizvanov, Regina R. Miftakhova
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:International Journal of Molecular Sciences
Subjects:
antibiotics
breast cancer
cancer stem cells
hypoxia
mitochondria
Online Access:https://www.mdpi.com/1422-0067/24/14/11540

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