Nrf2 affects hydroquinone-induces cell cycle arrest through the p16/pRb signaling pathway and antioxidant enzymes

Nrf2 affects hydroquinone-induces cell cycle arrest through the p16/pRb signaling pathway and antioxidant enzymes

Hydroquinone (HQ), a well-known carcinogenic agent, induces oxidative stress, cell cycle arrest, apoptosis, and malignant transformation. As an antioxidant actor, the nuclear factor erythroid 2-related factor 2 (Nrf2) drives adaptive cellular protection in response to oxidative stress. The human lym...

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Bibliographic Details
Main Authors: Lin Chen, Lu Zhai, Yuting Gao, Zheming Cui, Lingxue Yu, Delong Zhu, Huanwen Tang, Hao Luo
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Cell cycle
Hydroquinone
p16
Nrf2
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651322012295

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