Evaluation of plasma homocysteine status in streptozotocin induced-diabetes mellitus in rabbit
In this research, plasma homocysteine levels as an independent risk factor of cardiovascular disease was evaluated in streptozotocin induced diabetic New Zealand white rabbits. Twelve male New Zealand white rabbits were selected and allocated into two separate groups of test and control. Following c...
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| Format: | Article |
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Islamic Azad University, Tabriz Branch
2009-08-01
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| Series: | Āsīb/shināsī-i Darmāngāhī-i Dāmpizishkī |
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| Online Access: | http://jvcp.iaut.ac.ir/article_518680_981f6e4c57dd40c5d35b049b70ee3ea1.pdf |
| _version_ | 1818531241852403712 |
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| author | K Azimzadeh S Asri rezae Sh Safi I Sohrabi haghdoust M Ebrahimi hamed |
| author_facet | K Azimzadeh S Asri rezae Sh Safi I Sohrabi haghdoust M Ebrahimi hamed |
| author_sort | K Azimzadeh |
| collection | DOAJ |
| description | In this research, plasma homocysteine levels as an independent risk factor of cardiovascular disease was evaluated in streptozotocin induced diabetic New Zealand white rabbits. Twelve male New Zealand white rabbits were selected and allocated into two separate groups of test and control. Following confirmation of the rabbit’s health status (normal plasma glucose, urea and creatinine values), those in the test group received a single dose of streptozotocin at 65 mg/kg through the marginal ear vein while the control group were given normal saline solution. Blood samples were collected from the marginal ear vein after 24, 48 and 72 hours and then once every week for 12 weeks and plasma homocysteine, insulin and glucose levels were measured and statistically evaluated. The results indicated significant increase (p |
| first_indexed | 2024-12-11T17:29:54Z |
| format | Article |
| id | doaj.art-8aef1ecdb1164bd897320875bd1b68ad |
| institution | Directory Open Access Journal |
| issn | 2322-4746 2476-6984 |
| language | fas |
| last_indexed | 2024-12-11T17:29:54Z |
| publishDate | 2009-08-01 |
| publisher | Islamic Azad University, Tabriz Branch |
| record_format | Article |
| series | Āsīb/shināsī-i Darmāngāhī-i Dāmpizishkī |
| spelling | doaj.art-8aef1ecdb1164bd897320875bd1b68ad2022-12-22T00:56:52ZfasIslamic Azad University, Tabriz BranchĀsīb/shināsī-i Darmāngāhī-i Dāmpizishkī2322-47462476-69842009-08-0132 (10) تابستان445450518680Evaluation of plasma homocysteine status in streptozotocin induced-diabetes mellitus in rabbitK Azimzadeh0S Asri rezae1Sh Safi2I Sohrabi haghdoust3M Ebrahimi hamed4Department of Clinical Pathology, Faculty of Veterinary Medicine, Islamic Azad University, Science and Research Branch, Tehran, IranDepartment of Clinical Pathology, Faculty of Veterinary Medicine, Urmia University, Urmia, IranDepartment of Clinical Pathology, Faculty of Veterinary Medicine, Islamic Azad University, Science and Research Branch, Tehran, IranDepartment of Clinical Pathology, Faculty of Veterinary Medicine, Islamic Azad University, Science and Research Branch, Tehran, IranDepartment of Clinical Science, Faculty of Veterinary Medicine, Islamic Azad University, Urmia Branch, Urmia, IranIn this research, plasma homocysteine levels as an independent risk factor of cardiovascular disease was evaluated in streptozotocin induced diabetic New Zealand white rabbits. Twelve male New Zealand white rabbits were selected and allocated into two separate groups of test and control. Following confirmation of the rabbit’s health status (normal plasma glucose, urea and creatinine values), those in the test group received a single dose of streptozotocin at 65 mg/kg through the marginal ear vein while the control group were given normal saline solution. Blood samples were collected from the marginal ear vein after 24, 48 and 72 hours and then once every week for 12 weeks and plasma homocysteine, insulin and glucose levels were measured and statistically evaluated. The results indicated significant increase (phttp://jvcp.iaut.ac.ir/article_518680_981f6e4c57dd40c5d35b049b70ee3ea1.pdfDiabetes mellitusStreptozotocinHomocysteineRabbit |
| spellingShingle | K Azimzadeh S Asri rezae Sh Safi I Sohrabi haghdoust M Ebrahimi hamed Evaluation of plasma homocysteine status in streptozotocin induced-diabetes mellitus in rabbit Āsīb/shināsī-i Darmāngāhī-i Dāmpizishkī Diabetes mellitus Streptozotocin Homocysteine Rabbit |
| title | Evaluation of plasma homocysteine status in streptozotocin induced-diabetes mellitus in rabbit |
| title_full | Evaluation of plasma homocysteine status in streptozotocin induced-diabetes mellitus in rabbit |
| title_fullStr | Evaluation of plasma homocysteine status in streptozotocin induced-diabetes mellitus in rabbit |
| title_full_unstemmed | Evaluation of plasma homocysteine status in streptozotocin induced-diabetes mellitus in rabbit |
| title_short | Evaluation of plasma homocysteine status in streptozotocin induced-diabetes mellitus in rabbit |
| title_sort | evaluation of plasma homocysteine status in streptozotocin induced diabetes mellitus in rabbit |
| topic | Diabetes mellitus Streptozotocin Homocysteine Rabbit |
| url | http://jvcp.iaut.ac.ir/article_518680_981f6e4c57dd40c5d35b049b70ee3ea1.pdf |
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