Predicting combined antibacterial activity of sulfapyridine and its transformation products during sulfapyridine degradation
Antibiotics have strong antibacterial activity, even trace antibiotics can greatly inhibit the pollutant degradation efficiency. In order to effectively improve the pollutant degradation efficiency, it was hence of great significance to explore sulfapyridine (SPY) degradation and the mechanism of an...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-03-01
|
| Series: | Ecotoxicology and Environmental Safety |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0147651323001604 |
| _version_ | 1797869915956314112 |
|---|---|
| author | Pengcheng Yao Aiju You |
| author_facet | Pengcheng Yao Aiju You |
| author_sort | Pengcheng Yao |
| collection | DOAJ |
| description | Antibiotics have strong antibacterial activity, even trace antibiotics can greatly inhibit the pollutant degradation efficiency. In order to effectively improve the pollutant degradation efficiency, it was hence of great significance to explore sulfapyridine (SPY) degradation and the mechanism of antibacterial activity. This study selected SPY as the research object, of which the trend of SPY concentration through hydrogen peroxide (H2O2), potassium peroxydisulfate (PDS) and sodium percarbonate (SPC) and resultant antibacterial activity at pre-oxidation was examined. The combined antibacterial activity (CAA) of SPY and its transformation products (TPs) was further analyzed. The SPY degradation efficiency reached more than 90 %. However, the degradation efficiency of antibacterial activity was between 40–60 %, and the mixture’s antibacterial activity was difficult to be removed. The antibacterial activity of TP3, TP6 and TP7 was higher than that of SPY. TP1, and TP8 and TP10 were more prone to synergistic reaction with other TPs. The antibacterial activity of binary mixture gradually changed from synergism to antagonism as binary mixture concentration increased. The results provided a theoretical basis for the efficient degradation of antibacterial activity of the SPY mixture solution. |
| first_indexed | 2024-04-10T00:20:10Z |
| format | Article |
| id | doaj.art-8aef979fd7ce4c8fa2f123e962479e61 |
| institution | Directory Open Access Journal |
| issn | 0147-6513 |
| language | English |
| last_indexed | 2024-04-10T00:20:10Z |
| publishDate | 2023-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Ecotoxicology and Environmental Safety |
| spelling | doaj.art-8aef979fd7ce4c8fa2f123e962479e612023-03-16T05:01:14ZengElsevierEcotoxicology and Environmental Safety0147-65132023-03-01253114656Predicting combined antibacterial activity of sulfapyridine and its transformation products during sulfapyridine degradationPengcheng Yao0Aiju You1Zhejiang Institute of Hydraulics and Estuary (Zhejiang Institute of Marine Planning and Design), Zhejiang 311100, ChinaCorresponding author.; Zhejiang Institute of Hydraulics and Estuary (Zhejiang Institute of Marine Planning and Design), Zhejiang 311100, ChinaAntibiotics have strong antibacterial activity, even trace antibiotics can greatly inhibit the pollutant degradation efficiency. In order to effectively improve the pollutant degradation efficiency, it was hence of great significance to explore sulfapyridine (SPY) degradation and the mechanism of antibacterial activity. This study selected SPY as the research object, of which the trend of SPY concentration through hydrogen peroxide (H2O2), potassium peroxydisulfate (PDS) and sodium percarbonate (SPC) and resultant antibacterial activity at pre-oxidation was examined. The combined antibacterial activity (CAA) of SPY and its transformation products (TPs) was further analyzed. The SPY degradation efficiency reached more than 90 %. However, the degradation efficiency of antibacterial activity was between 40–60 %, and the mixture’s antibacterial activity was difficult to be removed. The antibacterial activity of TP3, TP6 and TP7 was higher than that of SPY. TP1, and TP8 and TP10 were more prone to synergistic reaction with other TPs. The antibacterial activity of binary mixture gradually changed from synergism to antagonism as binary mixture concentration increased. The results provided a theoretical basis for the efficient degradation of antibacterial activity of the SPY mixture solution.http://www.sciencedirect.com/science/article/pii/S0147651323001604SulfapyridineAntibacterial activityPro-oxidationAntagonistic reactionSynergistic reaction |
| spellingShingle | Pengcheng Yao Aiju You Predicting combined antibacterial activity of sulfapyridine and its transformation products during sulfapyridine degradation Ecotoxicology and Environmental Safety Sulfapyridine Antibacterial activity Pro-oxidation Antagonistic reaction Synergistic reaction |
| title | Predicting combined antibacterial activity of sulfapyridine and its transformation products during sulfapyridine degradation |
| title_full | Predicting combined antibacterial activity of sulfapyridine and its transformation products during sulfapyridine degradation |
| title_fullStr | Predicting combined antibacterial activity of sulfapyridine and its transformation products during sulfapyridine degradation |
| title_full_unstemmed | Predicting combined antibacterial activity of sulfapyridine and its transformation products during sulfapyridine degradation |
| title_short | Predicting combined antibacterial activity of sulfapyridine and its transformation products during sulfapyridine degradation |
| title_sort | predicting combined antibacterial activity of sulfapyridine and its transformation products during sulfapyridine degradation |
| topic | Sulfapyridine Antibacterial activity Pro-oxidation Antagonistic reaction Synergistic reaction |
| url | http://www.sciencedirect.com/science/article/pii/S0147651323001604 |
| work_keys_str_mv | AT pengchengyao predictingcombinedantibacterialactivityofsulfapyridineanditstransformationproductsduringsulfapyridinedegradation AT aijuyou predictingcombinedantibacterialactivityofsulfapyridineanditstransformationproductsduringsulfapyridinedegradation |