The Role of Cobalt Exposure in the Incidence of Cancer: A Systematic Review and Meta-Analysis Protocol
Background: Cobalt, a versatile transition metal, has widespread industrial applications, but its potential link to cancer has raised concerns. This systematic review and meta-analysis protocol aims to investigate the relationship between cobalt exposure and cancer incidence, addressing its implicat...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
West Asia Organization for Cancer Prevention
2023-09-01
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| Series: | Asian Pacific Journal of Environment and Cancer |
| Subjects: | |
| Online Access: | http://www.waocp.com/journal/index.php/apjec/article/view/1188 |
| _version_ | 1797328114195365888 |
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| author | Aram Halimi Mobina Karimiyan Tina Khavari Fatemeh Azizi Fatameh Asadipour Yaser Soleimani Alireza Mosavi Jarrahi |
| author_facet | Aram Halimi Mobina Karimiyan Tina Khavari Fatemeh Azizi Fatameh Asadipour Yaser Soleimani Alireza Mosavi Jarrahi |
| author_sort | Aram Halimi |
| collection | DOAJ |
| description | Background: Cobalt, a versatile transition metal, has widespread industrial applications, but its potential link to cancer has raised concerns. This systematic review and meta-analysis protocol aims to investigate the relationship between cobalt exposure and cancer incidence, addressing its implications for public health and occupational safety.
Methods: A comprehensive literature search will be conducted in PubMed, Scopus, and Web of Science databases up to August 2023. Eligible studies will include human participants exposed to cobalt, with cancer incidence as an outcome. Both observational and analytical study designs will be considered.
Results: Quantitative meta-analysis will be performed using random-effects models to calculate pooled Incidence Rate Ratios (IRRs). Subgroup and sensitivity analyses will explore heterogeneity and potential bias. Findings will be compared with prior research to assess consistency and support.
Conclusion: This systematic review and meta-analysis protocol aims to provide a comprehensive assessment of the potential association between cobalt exposure and cancer incidence. The outcomes could have significant implications for occupational health, public safety, and policy decisions. |
| first_indexed | 2024-03-08T06:47:17Z |
| format | Article |
| id | doaj.art-8af1548f2084412aad99d3d22647316a |
| institution | Directory Open Access Journal |
| issn | 2645-5404 |
| language | English |
| last_indexed | 2024-03-08T06:47:17Z |
| publishDate | 2023-09-01 |
| publisher | West Asia Organization for Cancer Prevention |
| record_format | Article |
| series | Asian Pacific Journal of Environment and Cancer |
| spelling | doaj.art-8af1548f2084412aad99d3d22647316a2024-02-03T07:33:19ZengWest Asia Organization for Cancer PreventionAsian Pacific Journal of Environment and Cancer2645-54042023-09-016113914510.31557/apjec.2023.6.1.139-1451188The Role of Cobalt Exposure in the Incidence of Cancer: A Systematic Review and Meta-Analysis ProtocolAram Halimi0Mobina Karimiyan1Tina Khavari2Fatemeh Azizi3Fatameh Asadipour4Yaser Soleimani5Alireza Mosavi Jarrahi6Student Research Committee, School of Public Health and Safety, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Department of Epidemiology, School of Public Health and Safety, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Department of Occupational Health Engineering, Student Research Committee, Sabzevar University of Medical Sciences, Sabzevar, Iran.Department of Occupational Health and Safety, School of Public Health and Safety, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Department of Occupational Health and Safety, School of Public Health and Safety, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Department of Occupational Health and Safety, School of Public Health and Safety, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Medical School, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Cancer Research Centre, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Background: Cobalt, a versatile transition metal, has widespread industrial applications, but its potential link to cancer has raised concerns. This systematic review and meta-analysis protocol aims to investigate the relationship between cobalt exposure and cancer incidence, addressing its implications for public health and occupational safety. Methods: A comprehensive literature search will be conducted in PubMed, Scopus, and Web of Science databases up to August 2023. Eligible studies will include human participants exposed to cobalt, with cancer incidence as an outcome. Both observational and analytical study designs will be considered. Results: Quantitative meta-analysis will be performed using random-effects models to calculate pooled Incidence Rate Ratios (IRRs). Subgroup and sensitivity analyses will explore heterogeneity and potential bias. Findings will be compared with prior research to assess consistency and support. Conclusion: This systematic review and meta-analysis protocol aims to provide a comprehensive assessment of the potential association between cobalt exposure and cancer incidence. The outcomes could have significant implications for occupational health, public safety, and policy decisions.http://www.waocp.com/journal/index.php/apjec/article/view/1188cancer research centre, shahid beheshti university of medical sciences, tehran, iran |
| spellingShingle | Aram Halimi Mobina Karimiyan Tina Khavari Fatemeh Azizi Fatameh Asadipour Yaser Soleimani Alireza Mosavi Jarrahi The Role of Cobalt Exposure in the Incidence of Cancer: A Systematic Review and Meta-Analysis Protocol Asian Pacific Journal of Environment and Cancer cancer research centre, shahid beheshti university of medical sciences, tehran, iran |
| title | The Role of Cobalt Exposure in the Incidence of Cancer: A Systematic Review and Meta-Analysis Protocol |
| title_full | The Role of Cobalt Exposure in the Incidence of Cancer: A Systematic Review and Meta-Analysis Protocol |
| title_fullStr | The Role of Cobalt Exposure in the Incidence of Cancer: A Systematic Review and Meta-Analysis Protocol |
| title_full_unstemmed | The Role of Cobalt Exposure in the Incidence of Cancer: A Systematic Review and Meta-Analysis Protocol |
| title_short | The Role of Cobalt Exposure in the Incidence of Cancer: A Systematic Review and Meta-Analysis Protocol |
| title_sort | role of cobalt exposure in the incidence of cancer a systematic review and meta analysis protocol |
| topic | cancer research centre, shahid beheshti university of medical sciences, tehran, iran |
| url | http://www.waocp.com/journal/index.php/apjec/article/view/1188 |
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