Unmet definitions in thromboprophylaxis for hospitalized medical patients: An appraisal for the need of recommendation

Abstract Up to about 60% of venous thromboembolic events in a community are associated with hospitalization, and most can be prevented by appropriate thromboprophylaxis. Several randomized clinical trials and guidelines have addressed the issue of thromboprophylaxis in hospitalized patients and reco...

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Main Authors: Bruno Ávila Ferreira, Marcos deBastos, Suely Meireles Rezende
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:Research and Practice in Thrombosis and Haemostasis
Subjects:
Online Access:https://doi.org/10.1002/rth2.12827
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author Bruno Ávila Ferreira
Marcos deBastos
Suely Meireles Rezende
author_facet Bruno Ávila Ferreira
Marcos deBastos
Suely Meireles Rezende
author_sort Bruno Ávila Ferreira
collection DOAJ
description Abstract Up to about 60% of venous thromboembolic events in a community are associated with hospitalization, and most can be prevented by appropriate thromboprophylaxis. Several randomized clinical trials and guidelines have addressed the issue of thromboprophylaxis in hospitalized patients and recommended strategies to assess patients' risk and thromboprophylaxis. Simple and validated risk assessment models are available to assist physicians in selecting patients who are at high risk for VTE, in whom thromboprophylaxis should be used. However, some concepts employed are imprecise or not appropriately defined. Indeed, there has been wide variation in the onset, duration, and adequacy of thromboprophylaxis, as well as in the definition of some risk factors. In this article, we highlight these issues and the unmet definitions in thromboprophylaxis in hospitalized patients mainly by addressing selected randomized clinical trials and guidelines.
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spelling doaj.art-8af2926562744a82a059fb429e28f7142023-08-02T06:44:47ZengElsevierResearch and Practice in Thrombosis and Haemostasis2475-03792022-10-0167n/an/a10.1002/rth2.12827Unmet definitions in thromboprophylaxis for hospitalized medical patients: An appraisal for the need of recommendationBruno Ávila Ferreira0Marcos deBastos1Suely Meireles Rezende2Faculty of Medicine Universidade Federal de Minas Gerais Belo Horizonte BrazilHospital Governador Israel Pinheiro Belo Horizonte BrazilFaculty of Medicine Universidade Federal de Minas Gerais Belo Horizonte BrazilAbstract Up to about 60% of venous thromboembolic events in a community are associated with hospitalization, and most can be prevented by appropriate thromboprophylaxis. Several randomized clinical trials and guidelines have addressed the issue of thromboprophylaxis in hospitalized patients and recommended strategies to assess patients' risk and thromboprophylaxis. Simple and validated risk assessment models are available to assist physicians in selecting patients who are at high risk for VTE, in whom thromboprophylaxis should be used. However, some concepts employed are imprecise or not appropriately defined. Indeed, there has been wide variation in the onset, duration, and adequacy of thromboprophylaxis, as well as in the definition of some risk factors. In this article, we highlight these issues and the unmet definitions in thromboprophylaxis in hospitalized patients mainly by addressing selected randomized clinical trials and guidelines.https://doi.org/10.1002/rth2.12827hospitalizationprophylaxisthromboprophylaxisthrombosisvenous thromboembolism
spellingShingle Bruno Ávila Ferreira
Marcos deBastos
Suely Meireles Rezende
Unmet definitions in thromboprophylaxis for hospitalized medical patients: An appraisal for the need of recommendation
Research and Practice in Thrombosis and Haemostasis
hospitalization
prophylaxis
thromboprophylaxis
thrombosis
venous thromboembolism
title Unmet definitions in thromboprophylaxis for hospitalized medical patients: An appraisal for the need of recommendation
title_full Unmet definitions in thromboprophylaxis for hospitalized medical patients: An appraisal for the need of recommendation
title_fullStr Unmet definitions in thromboprophylaxis for hospitalized medical patients: An appraisal for the need of recommendation
title_full_unstemmed Unmet definitions in thromboprophylaxis for hospitalized medical patients: An appraisal for the need of recommendation
title_short Unmet definitions in thromboprophylaxis for hospitalized medical patients: An appraisal for the need of recommendation
title_sort unmet definitions in thromboprophylaxis for hospitalized medical patients an appraisal for the need of recommendation
topic hospitalization
prophylaxis
thromboprophylaxis
thrombosis
venous thromboembolism
url https://doi.org/10.1002/rth2.12827
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AT suelymeirelesrezende unmetdefinitionsinthromboprophylaxisforhospitalizedmedicalpatientsanappraisalfortheneedofrecommendation