Emulsified nanoparticles containing inactivated influenza virus and CpG oligodeoxynucleotides critically influences the host immune responses in mice.

Emulsified nanoparticles containing inactivated influenza virus and CpG oligodeoxynucleotides critically influences the host immune responses in mice.

<h4>Background</h4>Antigen sparing and cross-protective immunity are regarded as crucial in pandemic influenza vaccine development. Both targets can be achieved by adjuvantation strategy to elicit a robust and broadened immune response. We assessed the immunogenicity of an inactivated H5...

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Main Authors: Ming-Hsi Huang, Su-Chen Lin, Chia-Hsin Hsiao, Hsin-Ju Chao, Hung-Ren Yang, Chien-Chun Liao, Po-Wei Chuang, Huang-Pi Wu, Chiung-Yi Huang, Chih-Hsiang Leng, Shih-Jen Liu, Hsin-Wei Chen, Ai-Hsiang Chou, Alan Yung-Chih Hu, Pele Chong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-08-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20808862/?tool=EBI

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