An updated review on animal models to study attention-deficit hyperactivity disorder
Abstract Attention-deficit hyperactivity disorder (ADHD) is a neuropsychiatric disorder affecting both children and adolescents. Individuals with ADHD experience heterogeneous problems, such as difficulty in attention, behavioral hyperactivity, and impulsivity. Recent studies have shown that complex...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2024-04-01
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| Series: | Translational Psychiatry |
| Online Access: | https://doi.org/10.1038/s41398-024-02893-0 |
| _version_ | 1797209075220480000 |
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| author | Daegeon Kim Dhananjay Yadav Minseok Song |
| author_facet | Daegeon Kim Dhananjay Yadav Minseok Song |
| author_sort | Daegeon Kim |
| collection | DOAJ |
| description | Abstract Attention-deficit hyperactivity disorder (ADHD) is a neuropsychiatric disorder affecting both children and adolescents. Individuals with ADHD experience heterogeneous problems, such as difficulty in attention, behavioral hyperactivity, and impulsivity. Recent studies have shown that complex genetic factors play a role in attention-deficit hyperactivity disorders. Animal models with clear hereditary traits are crucial for studying the molecular, biological, and brain circuit mechanisms underlying ADHD. Owing to their well-managed genetic origins and the relative simplicity with which the function of neuronal circuits is clearly established, models of mice can help learn the mechanisms involved in ADHD. Therefore, in this review, we highlighting the important genetic animal models that can be used to study ADHD. |
| first_indexed | 2024-04-24T09:48:56Z |
| format | Article |
| id | doaj.art-8af4fc7d56ad4b2c93a199f642465728 |
| institution | Directory Open Access Journal |
| issn | 2158-3188 |
| language | English |
| last_indexed | 2024-04-24T09:48:56Z |
| publishDate | 2024-04-01 |
| publisher | Nature Publishing Group |
| record_format | Article |
| series | Translational Psychiatry |
| spelling | doaj.art-8af4fc7d56ad4b2c93a199f6424657282024-04-14T11:30:02ZengNature Publishing GroupTranslational Psychiatry2158-31882024-04-0114111210.1038/s41398-024-02893-0An updated review on animal models to study attention-deficit hyperactivity disorderDaegeon Kim0Dhananjay Yadav1Minseok Song2Department of Life Science, Yeungnam UniversityDepartment of Life Science, Yeungnam UniversityDepartment of Life Science, Yeungnam UniversityAbstract Attention-deficit hyperactivity disorder (ADHD) is a neuropsychiatric disorder affecting both children and adolescents. Individuals with ADHD experience heterogeneous problems, such as difficulty in attention, behavioral hyperactivity, and impulsivity. Recent studies have shown that complex genetic factors play a role in attention-deficit hyperactivity disorders. Animal models with clear hereditary traits are crucial for studying the molecular, biological, and brain circuit mechanisms underlying ADHD. Owing to their well-managed genetic origins and the relative simplicity with which the function of neuronal circuits is clearly established, models of mice can help learn the mechanisms involved in ADHD. Therefore, in this review, we highlighting the important genetic animal models that can be used to study ADHD.https://doi.org/10.1038/s41398-024-02893-0 |
| spellingShingle | Daegeon Kim Dhananjay Yadav Minseok Song An updated review on animal models to study attention-deficit hyperactivity disorder Translational Psychiatry |
| title | An updated review on animal models to study attention-deficit hyperactivity disorder |
| title_full | An updated review on animal models to study attention-deficit hyperactivity disorder |
| title_fullStr | An updated review on animal models to study attention-deficit hyperactivity disorder |
| title_full_unstemmed | An updated review on animal models to study attention-deficit hyperactivity disorder |
| title_short | An updated review on animal models to study attention-deficit hyperactivity disorder |
| title_sort | updated review on animal models to study attention deficit hyperactivity disorder |
| url | https://doi.org/10.1038/s41398-024-02893-0 |
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