Validation of an LC-MS/MS Method for the Quantification of Caffeine and Theobromine Using Non-Matched Matrix Calibration Curve

Validation of an LC-MS/MS Method for the Quantification of Caffeine and Theobromine Using Non-Matched Matrix Calibration Curve

Caffeine is one of the most widely consumed psycho-stimulants. The study of the beneficial effects of caffeine consumption to decrease the risk of developing several neuropsychiatric pathologies is receiving increasing attention. Thus, accurate and sensitive methods have been developed, mainly by LC...

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Bibliographic Details
Main Authors: Vera M. Mendes, Margarida Coelho, Angelo R. Tomé, Rodrigo A. Cunha, Bruno Manadas
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Molecules
Subjects:
caffeine
LC-MS/MS
non-matched matrix calibration curve
Online Access:https://www.mdpi.com/1420-3049/24/16/2863

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