Case Report: Recurrent Autoimmune Hypoglycemia Induced by Non-Hypoglycemic Medications
We present a case of recurrent autoimmune hypoglycemia induced by non-hypoglycemic agents. We review reported cases of autoimmune hypoglycemia related to non-hypoglycemic agents, and discuss the effects of different detection methods for insulin autoantibodies on the results obtained. We aim to prov...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-07-01
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| Series: | Frontiers in Immunology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2022.855350/full |
| _version_ | 1817971202627469312 |
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| author | Qiuping Zhu Qiuping Zhu Hanxin Zhao Wei Qiu Fang Wu Chungen Qian Chungen Qian Yonghong Yang Ye Kang Fenping Zheng Jiaqiang Zhou |
| author_facet | Qiuping Zhu Qiuping Zhu Hanxin Zhao Wei Qiu Fang Wu Chungen Qian Chungen Qian Yonghong Yang Ye Kang Fenping Zheng Jiaqiang Zhou |
| author_sort | Qiuping Zhu |
| collection | DOAJ |
| description | We present a case of recurrent autoimmune hypoglycemia induced by non-hypoglycemic agents. We review reported cases of autoimmune hypoglycemia related to non-hypoglycemic agents, and discuss the effects of different detection methods for insulin autoantibodies on the results obtained. We aim to provide information for clinicians and a warning for medication usage. Considering the increasing number of clopidogrel-induced AIH cases and the hypoglycemia-induced increase in the risk of cardiovascular events, we recommend that cardiovascular disease patients being treated with clopidogrel be informed of this rare side effect and that clinicians be vigilant for the possibility of autoimmune hypoglycemia in this patient population. |
| first_indexed | 2024-04-13T20:43:39Z |
| format | Article |
| id | doaj.art-8af6ce4c6d754afe9cd8a58708a68c09 |
| institution | Directory Open Access Journal |
| issn | 1664-3224 |
| language | English |
| last_indexed | 2024-04-13T20:43:39Z |
| publishDate | 2022-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Immunology |
| spelling | doaj.art-8af6ce4c6d754afe9cd8a58708a68c092022-12-22T02:30:47ZengFrontiers Media S.A.Frontiers in Immunology1664-32242022-07-011310.3389/fimmu.2022.855350855350Case Report: Recurrent Autoimmune Hypoglycemia Induced by Non-Hypoglycemic MedicationsQiuping Zhu0Qiuping Zhu1Hanxin Zhao2Wei Qiu3Fang Wu4Chungen Qian5Chungen Qian6Yonghong Yang7Ye Kang8Fenping Zheng9Jiaqiang Zhou10Department of Endocrinology and Metabolism, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, ChinaDepartment of Endocrinology, Haining People’s Hospital, Haining, ChinaDepartment of Endocrinology and Metabolism, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, ChinaDepartment of Endocrinology, Huzhou Central Hospital, Huzhou, ChinaDepartment of Endocrinology and Metabolism, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, ChinaCollege of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, ChinaReagent R&D Center, Shenzhen YHLO Biotech Co., Ltd, Shenzhen, ChinaReagent R&D Center, Shenzhen YHLO Biotech Co., Ltd, Shenzhen, ChinaReagent R&D Center, Shenzhen YHLO Biotech Co., Ltd, Shenzhen, ChinaDepartment of Endocrinology and Metabolism, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, ChinaDepartment of Endocrinology and Metabolism, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, ChinaWe present a case of recurrent autoimmune hypoglycemia induced by non-hypoglycemic agents. We review reported cases of autoimmune hypoglycemia related to non-hypoglycemic agents, and discuss the effects of different detection methods for insulin autoantibodies on the results obtained. We aim to provide information for clinicians and a warning for medication usage. Considering the increasing number of clopidogrel-induced AIH cases and the hypoglycemia-induced increase in the risk of cardiovascular events, we recommend that cardiovascular disease patients being treated with clopidogrel be informed of this rare side effect and that clinicians be vigilant for the possibility of autoimmune hypoglycemia in this patient population.https://www.frontiersin.org/articles/10.3389/fimmu.2022.855350/fullhypoglycemiainsulin autoimmune syndromeinsulin autoantibodiesclopidogrelcase report |
| spellingShingle | Qiuping Zhu Qiuping Zhu Hanxin Zhao Wei Qiu Fang Wu Chungen Qian Chungen Qian Yonghong Yang Ye Kang Fenping Zheng Jiaqiang Zhou Case Report: Recurrent Autoimmune Hypoglycemia Induced by Non-Hypoglycemic Medications Frontiers in Immunology hypoglycemia insulin autoimmune syndrome insulin autoantibodies clopidogrel case report |
| title | Case Report: Recurrent Autoimmune Hypoglycemia Induced by Non-Hypoglycemic Medications |
| title_full | Case Report: Recurrent Autoimmune Hypoglycemia Induced by Non-Hypoglycemic Medications |
| title_fullStr | Case Report: Recurrent Autoimmune Hypoglycemia Induced by Non-Hypoglycemic Medications |
| title_full_unstemmed | Case Report: Recurrent Autoimmune Hypoglycemia Induced by Non-Hypoglycemic Medications |
| title_short | Case Report: Recurrent Autoimmune Hypoglycemia Induced by Non-Hypoglycemic Medications |
| title_sort | case report recurrent autoimmune hypoglycemia induced by non hypoglycemic medications |
| topic | hypoglycemia insulin autoimmune syndrome insulin autoantibodies clopidogrel case report |
| url | https://www.frontiersin.org/articles/10.3389/fimmu.2022.855350/full |
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