Actions of agonists and antagonists of the ghrelin/GHS-R pathway on GH secretion, appetite and cFos activity

Actions of agonists and antagonists of the ghrelin/GHS-R pathway on GH secretion, appetite and cFos activity

The stimulatory effects of ghrelin, a 28-AA acylated peptide originally isolated from stomach, on GH secretion and feeding are exclusively mediated through the growth hormone secretagogue 1a receptor (GHS-R1a), the only ghrelin receptor described so far. Several GHS-R1a agonists and antagonists have...

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Bibliographic Details
Main Authors: Rim eHassouna, Alexandra eLabarthe, Philippe eZizzari, Catherine eVideau, Michael D Culler, Jacques eEpelbaum, Virginie eTolle
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-03-01
Series:Frontiers in Endocrinology
Subjects:
Ghrelin
antagonist
food intake
cfos
GHS-R
agonist
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2013.00025/full

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