A Novel Mouse Model of Diffuse Intrinsic Pontine Glioma Initiated in Pax3-Expressing Cells
Diffuse intrinsic pontine glioma (DIPG) is a rare and incurable brain tumor that arises predominately in children and involves the pons, a structure that along with the midbrain and medulla makes up the brainstem. We have previously developed genetically engineered mouse models of brainstem glioma u...
Main Authors: | Katherine L. Misuraca, Guo Hu, Kelly L. Barton, Alexander Chung, Oren J. Becher |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2016-01-01
|
Series: | Neoplasia: An International Journal for Oncology Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1476558615001682 |
Similar Items
-
Pre-Clinical Models of Diffuse Intrinsic Pontine Glioma
by: Oren J Becher, et al.
Published: (2015-07-01) -
CDK4/6 and PDGFRA Signaling as Therapeutic Targets in Diffuse Intrinsic Pontine Glioma
by: Christine Hoeman, et al.
Published: (2018-05-01) -
Diffuse intrinsic pontine glioma: Poised for progress
by: Katherine eWarren
Published: (2012-12-01) -
A high-throughput in vitro drug screen in a genetically engineered mouse model of diffuse intrinsic pontine glioma identifies BMS-754807 as a promising therapeutic agent.
by: Kyle G Halvorson, et al.
Published: (2015-01-01) -
Pediatric diffuse intrinsic pontine gliomas
by: Huber Said Padilla-Zambrano, et al.
Published: (2019-01-01)